Bacteriophage uma: yokusetshenziswa, analogs kanye nokubuyekeza

Zokwelapha, Amagciwane ukudla isinqumo ukulwa ngosizo antibiotic, okuyinto ukubhubhisa eziyingozi kuphela kodwa kuyasizuzisa ezincane-eziphilayo. Akubona bonke odokotela ukukhumbula izidakamizwa ephephile - bacteriophages. Omunye bale mugqa coli bacteriophage. Ake sicabangele lokho luyindlela indlela yayo yesenzo, izinkomba kanye impendulo.

Bacteriophages - kuyini?

namagciwane abangela izifo kungenteka uhlushwe egciwaneni kanye abantu SARS noma umkhuhlane. Lezi bacteriophages kukhona amagciwane - ifomu ekuphileni acellular ehlanganisa ijazi amaprotheni kanye nucleic acid (RNA ne-DNA). Ngokungafani antibiotic, bacteriophages kudle kuphela uhlobo oluthile amagciwane. Ngakho-ke, linqume kubo kuphela ngemva ekutholeni uhlobo isifo lwegciwane.

A inzuzo enkulu Kuyaphawuleka ukuthi amagciwane musa ziba namandla okumelana bacteriophages. Lokhu ngenhlanhla ubhekwa isizathu esiyinhloko esenza nentshisekelo amagciwane amagciwane savuka muva. Nokho, phawula ukuthi imithi yesimanje iphathelene bacteriophages izidakamizwa immunobiological.

Amathuluzi Incazelo "Bacteriophage coli"

Isixazululo uketshezi lapho okuhlala umuthi angathengwa siqukethe filtrate fagolizata zamagciwane pathogenic ka E. coli.

Umuthi kunomphumela ethize futhi kubangela lysis (ukuphazamiseka) amaseli-bacterium Escherichia coli. Nucleic acid lingena singene ufuzo amagciwane iqala nokuzala ngokwayo. Phages okuyinto ligcwala iseli edwengula ke kusukela ngaphakathi bathuthela "isisulu" ezayo. Ngakho-ke, ngisho noma inombolo encane bacteriophages kungenzeka ukufezekisa lokhu kwakuyoba nomphumela omuhle yokwelapha.

Bacteriophage uma ezivezwa inkampani yasekhaya ezithaka imithi "Microgen". Isixazululo zingathengwa amabhodlela 20 ml noma 100 ml. Njengoba nemiyo ezengeziwe wokuqamba asetshenziswe hinozol.

izinkomba

izidakamizwa elwa namagciwane ngokuvamile iqondiswa ngaphandle kokuqale kufake izitshalo ukucacisa uhlobo ejenti, sithembele anhlobonhlobo imiphumela ye nomuthi. Kasibili kungenzeki ngaphansi kwezimo ezifanayo ezisetshenziselwa ukwelapha i bacteriophage. Escherichia coli - uhlobo eyinhloko namagciwane abangela izifo okuyiwona ingase imithi abathintekayo. Ngakho-ke, umuthi kumele isetshenziswe kuphela e izifo ezithathelwanayo odalwe lolu ejenti.

Linqume izidakamizwa ngenxa nokwelashwa izifo elandelayo:

• ENT zokugula Lokudabuka webhaktheriya (otitis abezindaba, namathansela, pharyngitis, sinusitis, sinusitis);
• zokuphefumula ipheshana isifo (ukucinana kwemigudu yokuphefumula, inyumoniya, laryngitis, tracheitis);
• ukunqoba amabhaktheriya emathunjini ipheshana wokugaya ukudla (dysbacteriosis, cholecystitis, gastroenterocolitis);
• isikhumba ukuvuvukala kanye nezifo kuhlinzwa (ukusha, bursitis, suppuration amanxeba, ithumba, mastitis, ithumba);
• pheshana urinary nezifo (pyelonephritis, cystitis oyingozi futhi ezingalapheki, urethritis);
• isifo zangasese (endometritis, coleitis, salpingo).

Ngokuba nokuvimbela isixazululo ukutheleleka "Bacteriophage uma" manual uncoma ukusetshenziswa ekwelapheni esikhumbeni ngemva kokuhlinzwa. Ngaphambi kokusebenzisa umkhiqizo kubalulekile ukunquma lwegciwane fagochuvstvitelnost.

Yokusetshenziswa

Izindlela ketshezi ingase isetshenziselwe temlomo lefanele, kunika tihlokwana, abaphathi rectal. Futhi isixazululo ukuze liphume igazi izimbobo emazinyweni, nezinhlelo zokusebenza wokunisela. Kwezinye izimo, umuthi kufanele lisetshenziswe futhi ekwelapheni ngezihloko ezihlukene amasayithi ukuvuvukala. Ngokungafani antibiotic, ukwelashwa bacteriophage ihlala phakathi nezinsuku ezingu-7 kuya ku-20.

isixazululo Oral okuboniswa cystitis, pyelonephritis futhi urethritis. Lapho amanzi kwesinye noma ukhalo kwezinso izidakamizwa iqondiswa nge tube abakhwabanisi. eboniswe Ngaphakathi bafake iziguli 20-30 ml abaneminyaka engama 8. Esikhathini ingaphakathi kwesinye Ungafaka-30 ml, futhi ukhalo - ka 6-7 ml ngosuku.

Phatha bacteriophage uma kungenzeka by nokugeza, rinsings futhi instillation izifo ENT. imithi ikakhulukazi ngempumelelo uma iqondiswa uye turundae ofakwe isixazululo ngendlela acinene noma umgodi ngokuhleba.

Bacteriophage uma dysbacteriosis nezinye pathologies ka ipheshana wokugaya ukudla okufanele zithathwe ngomlomo 20-30 ml kathathu ngosuku, ngoba okungenani ibe ihora elilodwa ngaphambi kokudla. Isikhathi yokwelapha ezinjalo - 3 amaviki.

izifo gynecological bemvelo ezithathelwanayo iphathwa ngokwethula ikhambi esithweni sowesifazane noma kwesibeletho. Ukuze uthole eyamukelayo olulodwa zidinga 5-10 ml isixazululo. Lapho wokufaka coleitis kufanele kube kabili ngosuku.

Ngemva lokuchitha ukulungiselela ithumba ingaphakathi iqondiswa e isamba lincane inani ubomvu akude. Bacteriophage futhi batheleka 10-20 ml nilimaza osteomyelitis amanxeba emva processing ezifanele.

ukusetshenziswa Pediatric

usizo oluyilo ezinkantolo kungaba ekwelapheni seziguli ezisencane. Bacteriophage coli kumele kusetshenziswe at dysbacteriosis, enterocolitis kubangelwa ukutheleleka nge Escherichia coli. Isixazululo kufanelekile ekwelapheni ababelethwa kungakafiki isikhathi ngisho. Ezimweni eziningi, imithi isetshenziswa ngendlela enemas okusezingeni eliphezulu, ethula isixazululo ngepayipi igesi noma ipayipi. Inqubo liphindwe izikhathi 2-3 ngosuku, usebenzisa ngayinye ethola elingekho ngaphezu kuka 10 ml ketshezi.

ekuphathweni Oral kungenzeka kuphela uma ingane akusho ahlupheke regurgitation njalo. Ikhambi Ngaleso exutshwe esincane ubisi lwebele. Ubude besikhathi sokwelashwa - izinsuku 5-15. Uma kudingeka, bacteriophages kuhlangene nezinye izidakamizwa enqubeni ukwelashwa. Amagciwane uyakwazi amagciwane eziningana ukuthuthukisa nomphumela oqabulayo kwezidakamizwa ukwandisa abe nozwela eziphilayo pathogenic.

Izixwayiso

Qaphela ukuthi isitsha ne izidakamizwa ngemva ukuvulwa lungekho kusitoreji eside. Ngaphambi ngalinye ukusebenzisa, kufanele ayonyakaziswa hhayi hlola inzika okuqukethwe. Phambi zomuthi yokugcina akumele zisetshenziswe.

Ukuvula umfuma entsha kufanele kube ngokuvumelana nezimiso ezithile:

• ngaphambi kokuqala zokukhwabanisa kuyadingeka ukuze gezisisa izandla;
• ikhava zokuzivikela phezu isitsha ziphathwe isixazululo utshwala;
• Ususe cap, ingawuthinti ngesivalo;
• ukususwa ngephutha i-plug, kungenzeka ibekwe ngaphakathi etafuleni;
• Ungashiyi isitsha evulekile;
• Gcina imithi kuphela in the esiqandisini.

uketshezi eyanele kufanele kube isipetu oyinyumba ngokusebenzisa ukhokho. Ukuze inqubo ngamunye kumelwe sebenzisa isipetu entsha. Awukwazi ukushiya inaliti sezimoto.

analogs

TeMtsetfo E. coli kungenzeka ngokusebenzisa omunye bacteriophage. Coli amaprotheni bacteriophage iqukethe ingxenye Kunezinhlobo eziningi Proteus (mirabilis, vulgaris), kanye Escherichia coli. Umuthi iyatholakala njengoba isixazululo ketshezi, zahlanganiswa ngo amabhodlela 20 100 ml, kanye ngesimo amaphilisi.

Sebenzisa nomuthi kungaba yezifo ezihlukahlukene, ejenti causative-bacterium abalwe ngenhla. Tablets engasetshenziselwa ukwelapha ezinganeni enyakeni 1. Umthamo zomuthi kunqunywa kuncike Ihlahlubo yobudala lesiguli.

Bacteriophage uma: Izibuyekezo

Naphezu kweqiniso lokuthi bacteriophages kuyaqabukela esetshenziswa ekwelashweni izinqubo ezihlukahlukene ezithathelwanayo, akudingekile ukuba uchithe lolu hlobo kwemithi kanye makudle antibiotic. Ngokusho izimpendulo iziguli, bacteriophages bayakwazi ukuba babhekane ngisho abanezifo sokuvuvukala imvelaphi virus. Uma kudingekile, angase iqondiswa lihambisana ejenti elwa namagciwane ukuthuthukisa isenzo lakamuva.