"Amoxiclav 625": yokusetshenziswa, nozakwabo yangempela

Phakathi ejenti elwa namagciwane ekulungiseleleni "Amoxiclav 625" kobufakazi nesineke kanye nezifundiswa ukwambulwa kakhulu. Umuthi ubhekwa lo muthi obanzi kunayo futhi ngenxa yalokho hola ukuqashelwa ebanzi. Ngenxa ezahlukene imisebenzi, ukuphepha kwezingane nabesifazane lactating, "Amoxicillin-clavulanate" ihlanganisa cishe ngokuphelele emkhakheni enokwehla yokwelapha sinenkonzo yokunakekela iziguli emakhaya zokuphefumula kanye nezifo urinary.

Dedela Highlights futhi analogue

Ukulungiselela "Amoksiklav 625" ezivezwa Slovenian Lek futhi yamiswa njengoba izidakamizwa izidakamizwa esebenzayo aminopenicillin amoxicillin futhi clavulanic acid. Eyokuqala udlala indima-antibiotic kanye acid zivikela webhaktheriya beta-lactamases. Njengengxenye 'Amoksiklav 625 mg "amaphilisi izidakamizwa zimumethe 500 mg elwa namagciwane, futhi 125 mg nezinsizasenzo clavulanate.

Ukulungiswa nge esebenzayo izidakamizwa amoxycillin okukhiqizwa ngaphansi kokuqondisa ezihlukahlukene amagama. Qualitative kakhulu analogue ziya okulandelayo evikelwe aminopenicillin "Amoklav", "Augmentin", "Flemoklav", "Amklav", "Farmentin", "Amoksikar Plus", "engeza", "Medoklav". Kukhona futhi penicillins olungavikelekile, okuyizinto analogue ngezigaba "Amoksiklava": "Amoxicillin", "Amoksikar", "Amosin", "Hikontsil" nabanye. kahle labo ubhekwa mayelana efanayo.

Ukuhlobana izidakamizwa

On the ukulungiselela "Amoxiclav 625" amazwana kusukela ochwepheshe sicacile. Lokhu nomuthi qualitative, omunye kuphela izidakamizwa temlomo elwa namagciwane izimpawu ongaphakeme engemihle. Ngenxa yalesi sizathu-ke isetshenziswa kuzo zonke izimo lapho amoxicillin sasifaneleka. Futhi "Amoxiclav" imelele izidakamizwa kuhlanganiswe. It ivikelwe clavulanic acid ngu penicillinase, i-enzyme ukuthi ebhubhisa lactam indandatho we-antibiotic. Siyabonga lokuvikeleka kwezifiso ezisemqoka "Amoxiclav" babeba matasa maqondana amaseli amagciwane abe nenkani.

ubufakazi

Njengoba unamathele izidakamizwa "Amoxiclav 625" manual iqukethe ngemihlahlandlela izifo ezithathelwanayo, ekwelapheni lapho ovunyelwe ukusebenzisa ama-antibiotic. Lokhu zokuphefumula ngokuvamile asathuthuka, emathunjini, izifo genitourinary of kobukhulu okuncane noma okusesilinganisweni. Ngo amafomu onomoya omnene ka monotherapy ezifanele, kuyilapho nokulinganisela ezinzima kumele baphathwe izigceme inpatient inhlanganisela antibiotic. Ngokuvamile, izinkomba ukusetshenziswa "Amoxiclav 625 mg" ukulungiselela Umhlahlandlela uchaza kanje:

• izifo elingenhla izitho zokuphefumula (chronic amafomu okukhulu namathansela, pharyngitis, sinusitis, abezindaba otitis);
• izifo ezithathelwanayo we ephansi zokuphefumula ipheshana izifo (amafomu oyingozi futhi ezingalapheki Ukucinana kwemigudu yomoya emaphashini, inyumoniya);
• izifo ezibangelwa amagciwane kohlelo urogenital (pyelonephritis, urethritis, cystitis, oophoritis, ukuvuvukala okhalo, endometritis, isipatsholo, chancroid);
• osteomyelitis ezingamahlalakhona;
• tesikhumba, itheleleke isilwane Ukulunywa, ikoloni nilimaza amagciwane;
• periodontitis.

Ukuze isiguli, umthombo oyinhloko ulwazi mayelana "Amoxiclav" ukulungiselela - imfundo manual. 625 mg ketshezi izidakamizwa, okhethwe triplicate umuntu omdala, ungakwazi aphathe ngempumelelo izifo umgudu wokuphefumula kubangelwa igremu-HIV advantageously flora. Futhi Ari isikhathi ukwelashwa ngokuvamile 5-7 izinsuku.

Izimo

irekhodi ukuphepha Umuthi futhi ongaphakeme ubuthi ekilasini penicillin akusho ukubeka eceleni khona Izimo.

Banezinhliziyo imithi kancane. Zihlobene noma yokubakhona izifo concomitant, ukusabela iguliswa noma isimo bokuphila we umzimba. Izimo zihlanganisa:

• ukutholakala okubonisa okuvela jaundice cholestatic, kukhuphuke aminotransferase umsebenzi noma ukuthuthukiswa kwesibindi ukusebenza okubangwa yileli hlelo ekuqaleni "Amoksiklava", analogs yayo noma abamele iqembu penicillins;
• esingamahlalakhona hepatic, wegazi lymph, mononucleosis ngenxa eziya ziba zimbi yenomboro nobukhali side effects;
• sensitization iguliswa izidakamizwa noma izingxenye zalo;
• izinkomba ukuvela uhlobo ngokushesha komzimba uma nithatha namanye amanxusa beta-lactam elwa namagciwane;
• isihlobo isikhathi Izimo: kwabakhulelwe senyanga 3rd lactation.

Ingozi komzimba ekuthuthukiseni

Uma umlando lesiguli kukhona ukubhekisela uhlobo endawo njengemithi yokungezwani komzimba nokuthile, "Amoxiclav" ayizange inikezwe. Uma athuthukile anaphylaxis noma angioedema ekuphenduleni ethola namanye amanxusa beta-lactam elwa namagciwane, i- "Amoxicillin-clavulanate" Kufanele futhi ngeke amukelwe. Khona-ke lo muthi oluthandwa imelele eziningi macrolides enkambweni ngokulinganisela, noma fluoroquinolone.

Umthamo zemithi

Inani izidakamizwa "Amoksiklav 625 mg," esidingeka ukuphathwa incike yobudala kanye nesisindo isiguli. izifo zokuphefumula enomqondo nika up 2 amagremu abadala kanye 1.3 amagremu nentsha ingafaneleki. I "Amoxiclav" at umthamo 625 mg iyona kuphela ingane futhi omdala izidakamizwa. Izingane ezingaphansi kweminyaka engu-12 ubudala, kukhona ukudla izidakamizwa ngineminyaka ngemithamo aphansi.

Isikali Standard for umuntu enesisindo 40 kg futhi engaphezu kwengu-12 ubudala kuyinto 625 mg kabili ngelanga. Abadala abaneminyaka engu 18 enqunyiwe 625 mg kathathu ngosuku. Lokhu kwanele ekwelapheni ngokulinganisela nokukhanya, okungukuthi, sinenkonzo yokunakekela iziguli izifo zesikhumba, zokuphefumula, uhlelo urogenital. Ngo ngamagciwane okunzima babelwe 1000 mg (875 mg amoxycillin futhi clavulanate 125) kabili ngelanga. Ivunyelwe mithathu isicelo 1000 mg.

isicinganani

Naphezu ububanzi ezanele isinyathelo zokwelapha, baba baningana amathuba okuba nemiphumela engemihle. Basuke ezihambisana iziyaluyalu endawo imisebenzi emathunjini bese esiswini, kanye ngenxa imikhiqizo ukudakwa kwamazinyo lamaseli webhaktheriya, njengoba umphumela umuthi olwa namagciwane amagciwane.

I njalo kunazo (1-10%) kukhona amacala isicanucanu, ukuhlanza noma isifo sohudo okwenzeka ngemva isicelo ye-ejenti elwa namagciwane. Futhi avele 2-4 izinsuku emva yokwemukelwa. Kuyaphawuleka kukhulisa ematfuba dyspepsia ukuphazamiseka ekhona kakade wamathumbu imikhuba, futhi ezinye izifo ohambisana: pancreatitis nge esingamahlalakhona excretory, isimo enteritis ngemva resection isisu noma ezikhulula, nesifo esingamahlalakhona.

Iqembu yezinkinga ukungasebenzisi (0,001-0,0001%) kukhona izinkinga zesibindi: transaminases anda nezimpawu of hepatocyte cytolysis, cholestasis kanye jaundice, leukopenia. I angioedema imvamisa, urticaria futhi anaphylaxis olungacaciswanga. Isizathu salokhu iyona ukwenyuka kancane isibalo komzimba ngenxa sensitization ekuseni kwezingane.

Kamuva, kuyoba nakanjani kuyoholela nokuncipha ukubaluleka izidakamizwa zokwelapha "Amoxiclav". Yokusetshenziswa ithebhulethi 625-mg ayikahlanganiswa kungavunyelwe ukusetshenziswa nabancelisayo. Nokho, lokhu kungase MADUZE kuzokwenzeka. Khona-ke kudingeka afune umuthi omusha amino nge kahle efanayo. Ngokwemvelo, ukuthi entsha chemical izidakamizwa iye kwemiqondo futhi zivivinywe, kodwa nokuqaliswa kwalo kuze kwezomnotho disadvantageous, ngoba "Amoxiclav" ihlangabezana nezidingo odokotela.

Reception phakathi nokukhulelwa kanye lactation

Ngokusho ulwazi FDA, "Amoxiclav" ayinayo nomphumela teratogenic. Lesi siphetho yathinteka ngemuva kokwenza ucwaningo ezilwaneni, ngoba zonke analogue zomuthi kufakwe Isigaba B ngu-FDA (USA). Nokho, ngenxa yokwesaba okunengqondo zimbi toxicosis "Amoxiclav 625" ngesikhathi sokukhulelwa cishe hhayi zinikwa senyanga yokuqala. Ngo II no III trimesters reception yayo kuvunyelwe.

Aminopenicillin e trace kufana ku ubisi lwebele, okuyinto bawe pheshana emathunjini ngayo lapho usana. Nokho, ukwephula abalulekile emzimbeni wakhe, khona-ke aluphumeleli kubangele, ngenxa yalokho "Amoxiclav 625" Awukwazi ukukhansela ngesikhathi lactation. Okukhishwayo kuphela izimo komzimba nezinto kwengane noma vulvovaginal nolwelwesi lwamafinyila noma ipheshana wokugaya ukudla, okuholela isicelo "Amoxicillin". Khona-ke sidinga noma ukuqedwa unina ethola umenzeli elwa namagciwane, noma - at mucosal candidiasis - hhayi ukuba bancelise.

izidakamizwa ukuphepha isici

Tablets "Amoxiclav 625" kukhona spectrum okunengqondo ezibanzi yesenzo zokwelapha, kanjalo sigweme ubuthi. Futhi, ayinayo imiphumela emaphakathi, ngenxa yalokho kungenziwa inikezwa iziguli ukuthi ngubani osebenzisa imoto noma ezinye izindlela ezihambayo. Yena aliholeli ukwephula inkumbulo, ukwazi, ukunakwa, noma ukucabanga.

Nokho, kukhona ukweqisa izidakamizwa syndrome izidakamizwa. Ezimweni ezinjalo ezingavamile, futhi kwenzeka ngokukhethekile ezimweni engafanele umthamo owodwa we-5 noma ngaphezulu amagremu zomuthi. Izimpawu yilezi izici ezilandelayo: iziyaluyalu sohudo elihlobene ne kobukhulu ubuhlungu besisu, ukuvuvukala nohudo, ukucanuzela kwenhliziyo futhi ngezinye izikhathi nokuhlanza.

Kukhona amacala crystalluria, ngokumitha kwemihlambi ngaphakamisa edonsa amoxicillin, ngezinye izikhathi kubangele ukuthuthukiswa ukwehluleka kwezinso. Nokho, lesi simo singenzeka uma wamukela Isikali zokwelapha zomuthi. Kusho ukwelashwa nefroprotektsiya futhi isebenzisa umshini wezinso, ivumela ukuba ususe kusukela egazini lika-amoxicillin futhi clavulanic acid.

izinyathelo zokuqapha

Iziguli, ene-leukemia lymph, noma ezithathelwanayo mononucleosis izidakamizwa "Amoksiklav 625", analogs kanye imithi ejwayelekile kungaveli ngenxa amathuba eliphezulu morbilliform ngamawala. Futhi ngenxa ukwehla ukusebenza kwe zokuvimbela inzalo temlomo ngesikhatsi ukwelashwa "Amoxicillin" kuyadingeka ukuze umphelelisi isivikelo engadingeki izindlela sokukhulelwa isithiyo (amakhondomu).

With ukuthuthukiswa sohudo phakathi kokusebenza "Amoksiklava" idinga ukususwa lo muthi kanye nokwelashwa yesifo (pseudomembranous noma oluhambisana). Kulesi simo, isicelo inadmissible "Loperamide". Futhi, isicelo eside "Amoksiklava" kunomthelela ukuthuthukiswa amakoloni eziningi microbial ziyawathinta antimicrobial. Zingadala yezinkinga yalesi sifo.

Akwaziwa izidakamizwa ekuhlanganyeleni

Urikozostatichesky izidakamizwa "allopurinol" edilini lomshado kanye "Amoksiklava" kwandisa ingozi ukuqubuka. urikozuricheskogo Isicelo kusho "Probenecid", "oxyphenbutazone," "Phenylbutazone", "sulfinpyrazone" noma acetylsalicylic ene-asidi anciphisa ukwabiwa aminopenicillin (kodwa hhayi clavulanic acid), ngenxa okuyinto kancane kwandisa lokuhlushwa-antibiotic e igazi serum nokulondoloza imiphumela yayo.

Inhlanganisela izidakamizwa "Amoksiklav 625 mg" nge-antimicrobial bacteriostatic engenangqondo ngenxa mutual ukucindezelwa kahle yabo. Okunye amalungiselelo equkethe amoxicillin, futhi kufanele kuhlanganiswe bacteriostatic: chloramphenicol, macrolides, tetracyclines kanye sulfonamides. Inhlanganisela ngemithi elwa namagciwane amagciwane kuholela ukwanda mutual umsebenzi elwa namagciwane.

Sebenzisa "Amoxiclav" ngesikhathi yokwelapha, izinto zokuvimba inzalo temlomo okulahlwayo ngenxa ingozi lenyuka prothrombin isikhathi thrombosis. Kulesi ukusebenza umuthi is kakhulu ziyancipha. Okunye ezibanzi spectrum imithi elwa namagciwane futhi sokulamula umphumela ukunciphisa ukusebenza amalungiselelo temlomo umuthi.

Ukusetshenziswa "Amoksiklava" oportunisticheskih ukuze yelaphe izifo ezibangelwa ezivukayo on isizinda yokwelapha methotrexate, kakhulu kwandisa ubuthi lakamuva. Lokhu kukhulisa ematfuba thrombocytopenia, leukopenia, izilonda isikhumba, izilonda emathunjini bese erosions. Khona-ke Kunconywa ukuba bangayeki aminopenicillin ukusetshenziswa macrolides, Ngokuqhubeka okunye ukwelashwa nge methotrexate.

Njenganoma iyiphi imithi elwa namagciwane ezibanzi-spectrum, "Amoxiclav" kwandisa ukusebenza kahle ka anticoagulants engesobala. Ukwelashwa "warfarin" ngenxa yokucindezelwa ejenti elwa namagciwane kusukela amagciwane synthesize vitamin K kuholela ukwehla prothrombin Inkomba kanye INR anda. Umphumela nengozi enkulu ebangela ukopha.

Izici of the kuhlangene yokwelapha elwa namagciwane

Izidakamizwa "Amoxiclav 625" kanye nozakwabo yayo ejwayelekile unekhono sandise amathuba isifo sohudo, uma esetshenziswa namanye amanxusa imithi elwa nawo. Noma yimuphi amakilasi kwamaphilisi kanye amoxicillin kakhulu maningi amathuba okuthi isifo sohudo, okungakwazi aphathwe ngosizo peristalsis ezicindezelayo. ukulungiselela okunjalo "loperamide" futhi analogue yayo, contraindicated ngo sohudo ezithathelwanayo. Kulokhu, uhudo kubangelwa ukusetshenziswa "Amoksiklava" kufanele aphathwe ngemithi elwa namagciwane.