"Aklasta": ukubuyekezwa, yokusetshenziswa, analogs

Zonke kudale tinkinga letinyenti namuhla, imizamo eminingi ukuze bathuthukise impilo yabo. Ukuguga, nensada nokucindezela isifo esingelapheki kuyinto nomthelela omubi kakhulu ku isimo jikelele zomzimba womuntu futhi zibangele ukubukeka izifo ezintsha ezingaphezu nokuningi. Ikakhulukazi ngempela izinkinga nge uhlelo zemisipha. Iningi leziguli abanawo emzimbeni yabo eziningi ezanele izidubedube ukuze wakwati kubeketelela bumatima. Yingakho izimo ezinjalo ezihlobene lapho kubhujiswa nezicubu ithambo, ngokuvamile kuphela wawuhlanganisa ngokuhamba kwesikhathi.

Ngenhlanhla, imithi yesimanje ithole eziningi ngamathuba okwenza ngcono izinga lempilo salezi ziguli. izidakamizwa Ngisho yakhelwe ukuba iphathwe kanye kuphela ngonyaka. Umthelela izidakamizwa ezifana ngokwanele ukuba azizwe engcono kuze inqubo elandelayo. Omunye izidakamizwa ezinjalo kuba "Aklasta". Abaningi bayakwazi ukuhlola lonke spectrum imisebenzi yayo. Kusemqoka ukuthi iziguli ezingaba ibilokhu wafunda lonke ulwazi olutholakala ku-umkhiqizo zokwelapha "Aklasta": yokusetshenziswa, nozakwabo yangempela. Lokhu kuzovumela ke ukuqinisekisa ukusebenza yayo, ahlaziye kahle zonke izingozi isikhonzi kanye izimo kanye zizenzele esazo isinqumo unolwazi ukuthi zinjalo yini ukusebenzisa izidakamizwa okukhulunywa kuwufanele.

izinkomba

Kwezinye izimo, kungaba ukuhlakanipha ukusebenzisa izidakamizwa "Aklasta"? Imiyalelo, ukubuyekeza umbiko edingida izidakamizwa ngempumelelo kwalezi zimo:

• ukuqaliswa nokuvinjelwa waphuka entsha ezigulini kakade senihluphekile ukwaphuka we kunawo wonke (ie ingxenye proximal ngakho);
• Paget (bone) isifo;
• ukukhumuzeka kwamathambo (ikakhulukazi iziguli besilisa);
• zokuvimbela nokuthuthuka iziguli besifazane abaphethwe osteopenia, ukukhumuzeka kwamathambo postmenopausal;
• ngqo kwamathambo postmenopausal (ukulungiselela ihlinzeka ukunciphisa okuphawulekayo ingozi waphuka sina, waphuka of kunawo wonke, kanye amathambo ngabanye kanye waphuka ngisho vnevertebralnyh; izidakamizwa kakhulu kwandisa kwabantu ithambo amaminerali);
• esetshenziselwa nokwelashwa kwamathambo yokuthi esakhiwe ngaphansi kwethonya isicelo glucocorticosteroids.

Izimo

Ingabe wonke umuntu ukusebenzisa izidakamizwa "Aklasta"? Uphenyo odokotela etshela ukuthi izidakamizwa kubhekwe anezinye Izimo sina. ikakhulukazi phakathi kwabo kukhona lokhu okulandelayo:

• inkathi sokukhulelwa wengane;
• ukuzwela ePhakeme ukuba siqu zoledronic acid, kanye neminye imithi yezingxenye ngazinye;
• uncelisa ingane;
• iyiphi ukuhlanekezela inqubo amaminerali umzimba (sifo obujwayelekile hypocalcemia);
• isiguli okungalungile ubudala (ukuphepha nokusebenza ngempumelelo yokusebenzisa izidakamizwa ngaphansi ukucatshangelwa kwafakazelani for iziguli engamahlongandlebe);
• izinso abahluphayo operation (of kobukhulu obuhlukahlukene).

Ephambi kwezinduna okungenani eyodwa yale mibandela engenhla kubalulekile ukuba uqale ukusebenzisa izidakamizwa "Aklasta". Ukubuyekezwa (abaphuza umuthi sitshele kusuka isipiliyoni sami siqu) ukubika ukuthi ukusetshenziswa le-ejenti ukuze iziguli Izimo kungaholela ziwohloke abukhali. Kumelwe ithathelwe isikhundla umuntu ofanelekile ukuba ayothatha.

nokushintsha kokudla nokufakwa

Njengoba izidakamizwa kumele kusetshenziswe ehilelekile? Iqondiswa ngemithambo yegazi. Ngenxa yale njongo, valve ukumnika uhlelo enikeza unomphela ukumnika izinga. Inqubo kuthatha imizuzu eyishumi nanhlanu. Kubalulekile ukuthi isiguli isikhathi esithile ngaphambi kokuba ukwelashwa waqala ukusebenzisa isamba elanele kwamanzi aphephile okuphuza.

Ngakho, ukubhekana abesifazane post-menopausal nge kwamathambo kanye wesilisa kwamathambo ezinqunyiwe umthamo ukusebenza izidakamizwa ngaphansi ukucatshangelwa - angu ezinhlanu (ngesikhathi nanye, njengoba umthetho, iqukethe eziyikhulu namamililitha). Inqubo wenziwa kanye kuphela ngonyaka. Ngezinye izikhathi udokotela ekwelapheni ibona kunesidingo salokhu ukuqoka engayitholi ezengeziwe calcium ne kavithamini D. Kungokufanayo zokusebenza umthamo engabelwe nokuvimbela waphuka yansukuzonke bone uphawu esikhathini postoperative, futhi ulwe nesifo ithambo Paget sika.

Labo iziguli abaphethwe kwezinso noma isibindi ukusebenza, akudingeki ukuba nabo ngqó sibuyekezwe abasebenzi ekuqaleni babelwe ulapha. Ngokufanayo, kukhona isimo nge ezigulini esezikhulile (kabani yobudala, ikakhulukazi, eminyakeni engaphezu kwengu-65). Ubudala ingadlali indima ebalulekile indlela izidakamizwa usebenza emzimbeni nendlela basakaza futhi zithutha.

Uma usebenzisa izidakamizwa kokubuyekezwa, kubalulekile ukuhambisana nayo yonke amazinga aseptic ekhona. Kusho ukuthini lokhu? Kuyadingeka ngaphambi kokuqhubeka ne ukwethulwa izidakamizwa, cabangisisa okuqukethwe isitsha futhi ahlaziye ukuthi ikhwalithi umbala ikhambi isicelo. Uma uqaphela ushintsho umbala noma ezivele inzika, ungasebenzisi leli thuluzi. "Aklastu" iqondiswa ngokuhlukile zonke ezinye izidakamizwa. Ngeke exutshwe nezinye izidakamizwa ngisho ukuvimbela imithi contact sakugcina ne izinto i-calcium.

Kubalulekile ukusebenzisa imithi ngokushesha ngemva ibhodlela uvulekele, lapho wadedelwa. Uma ezinye ingxenye yesixazululo namanje abakwazi ukusebenzisa ngokushesha, kufanele igcinwe esiqandisini, kodwa hhayi isikhathi eside esingaphezu kosuku olulodwa. isitoreji lokushisa Allowable - ezimbili kuya ayisishiyagalombili degrees. Ngaphambi kokusebenzisa ikhambi elinjalo kubalulekile ukuxoxa it up, beletha ekamelweni lokushisa. Kuyadingeka ukuba amnike ithuba ukufinyelela ezingeni lokushisa elifanele.

side effects

Ngezinye izikhathi kungase kube imiphumela engasi mihle kusukela ukusetshenziswa kwezidakamizwa "Aklasta". Izibuyekezo futhi odokotela ukukhuluma ngalezi imiphumela engemihle engase ibe:

• hypomagnesemia;
• stomatitis;
• hypophosphatemia;
• isicanucanu;
• dyspepsia;
• hypocalcemia;
• ukuhlanza;
• eliqhaqhazelayo;
• ubuhlungu iso;
• Ubuhlungu obukhulu besisu,
• hyperkalemia;
• ukungakuthandi ukudla;
• ikhanda;
• iritis;
• paresthesia;
• isiyezi;
• hypokalemia;
• esophagitis;
• ukozela;
• conjunctivitis;
• ukuqunjelwa;
• hypernatremia;
• anaemia;
• bradycardia;
• uveitis;
• isifo sohudo,
• iziyaluyalu ubuthongo;
• inzululwane;
• hematuria;
• thrombocytopenia;
• iphika;
• ukucobeka;
• hypoesthesia;
• ukukhathazeka;
• ukwehluleka oyingozi kwezinso;
• yokufikelwa;
• leukopenia;
• amazinyo;
• ukulunywa;
• eliqhaqhazelayo;
• pancytopenia;
• umkhuhlane;
• hypersensitivity;
• imisipha amajaqamba;
• kome nolwelwesi lwamafinyila emlonyeni;
• ukuqubuka kwesikhumba;
• ukusebenza kwezinso;
• ukuvuvukala ngokuhlanganyela;
• angioedema;
• ngenxa yobuthakathaka;
• ukukhwehlela;
• nokwanda okuphawulekayo esisindo;
• uzizwa bomile;
• komzimba okungamahlalakhona;
• ukudideka;
• episcleritis;
• arthralgia;
• ubuhlungu endaweni esifubeni;
• proteinuria;
• osteonecrosis;
• ukubonakala izimpawu zomkhuhlane;
• ukwephulwa ukunambitheka ukuzwa;
• ossalgia;
• edema neuropathy;
• kwehle acuity ezibukwayo;
• asthenia;
• myalgia;
• ukujuluka owandiswayo;
• sokuzincisha;
• hypercreatininemia;
• ubuhlungu emuva, izingalo nemilenze.

Lapho okungenani ezinye zalezi zimpawu, uyeka ukuphuza umuthi futhi bafune usizo kudokotela wakho. Lo chwepheshe ayoyikhetha efanelekayo esikhundleni izidakamizwa "Aklasta". Uphenyo odokotela ukugcizelela ukubaluleka kwalesi sinyathelo. Le nqubo elula kungasiza ukuze ulondoloze impilo.

ukweqisa izidakamizwa

Kuze kube manje, omncane mayelana amacala ukweqisa izidakamizwa eyaziwa ngesikhatsi ukwelashwa nge "Aklasta". Izibuyekezo iziguli ukubika ukuthi abazincomayo igcinwe ngaphansi kweso onguchwepheshe, uma wamiswa umthamo imithi ingaphezu kwesilinganiso.

Ziyini izimpawu ngokweqile? Phakathi kwabo kukhona lokhu okulandelayo:

• hypophosphatemia;
• ukwehluleka oyingozi kwezinso;
• hypomagnesemia;
• hypocalcemia.

Njengoba Kunconywa ukuqeda izimpawu ukweqisa izidakamizwa ezenzeka phakathi ukusetshenziswa kwezidakamizwa "Aklasta"? Izibuyekezo odokotela luleka iqondiswa izixazululo ngemithambo yegazi ezithile ezingasetshenziswa ukusiza ekuvuseleleni izindawo yesimo esihle somzimba, njengokushaya isixazululo magnesium ion, i-calcium ne-phosphate. Le nqubo ngezinye izikhathi ukusindisa ukuphila lesiguli, ngakho-ke sebenzisa kumele kuphela onguchwepheshe.

Ukusebenzisana neminye imithi

Ngeshwa, kuze kube manje, ayizange izifundo sasivumela onegunya okwakuyosiza ukuze kufinyelelwe esiphethweni mayelana nokuthi isetshenziswa kanjani ngokuphepha izidakamizwa kanye nezinye izidakamizwa "Aklasta". Izibuyekezo belulekwa ukuba unaka noma ikuphi ukusabela bakwazi ukungena oyinhloko esebenzayo ingxenye - zolendronovaya acid. It is, eyaziwa akusiyo kuncike ezivamile uhlelo umzimba. Ingqikithi awuphumi ngokusebenzisa nezinso. Ngenxa yalokho, kubalulekile ukuba singavumeli ukusetshenziswa ngesikhathi esisodwa izidakamizwa, okwa- labo abazokwazi ngokuqondile noma ngokungaqondile sicindezeleke umsebenzi kwazo lezi zitho, kanye nalabo ezibanga excretion ketshezi asebenzayo kusuka umzimba (ikakhulu, isisu).

Izixwayiso

On ezicashile eziyisisekelo usebenzisa imithi nesineke kubhekwe kumele azise ochwepheshe ngaphambi kokuqala ukwelashwa. Ngokwesibonelo, kufanele utshele kanjani ligqugquzela calcium excretion of kwabathinta "Aklasta". Izibuyekezo ukhulume ukubonakaliswa abasafufusa of hypocalcemia. Yingakho yalezo ziguli basengozini kufanele njalo wawuqondiswa okhokhelwayo.

Iziguli bamathambo Paget, kufanele ukwelashwa kuphela ngaphansi kokuqondisa kukadokotela abanekhono, osevele unaso isipiliyoni eside ekwelapheni lesi sifo.

ochwepheshe abaningi bami kwelokuthi ekusetshenzisweni ibuprofen noma paracetamol ngokushesha ngemva umjovo we izidakamizwa ngaphansi ukucatshangelwa. Lokhu kuzosiza ukunciphisa ukungakhululeki ezenzeka phakathi nezinsuku zokuqala ezintathu emva ukumnika, njengoba umbiko lisho ukuthi "Aklasta" kobufakazi nesineke.

Imijovo "Zometa" (isidakamizwa anticancer), izidakamizwa esebenzayo eyinhloko futhi zolendronovaya acid awacatshangwa izidakamizwa esikhundleni. Akufanele sisetshenziswe ngokulinganisa. Uma isiguli uye kwatholakala hypocalcemia, ngaphambi kokuba baqale ukwelashwa nge izidakamizwa ngaphansi nokucabangela kufanele ubambe ukwelashwa okwengeziwe enqunywe udokotela wakho esenikwe uvithamini D, ne-calcium. Ngokufanayo, kubalulekile ukulungisa ezinye izimo ukutholakala libhekene iziyaluyalu amaminerali umzimba.

Okumele kuqashelwe kufanele ukuqhuba seziguli asebavele eningi kwalo ukusebenza kwezinso.

Kubalulekile ukukhumbula ukuthi akukho ukwaziswa okunokwethenjelwa mayelana nendlela kwethonya elinamandla le izidakamizwa has ekhonweni lesiguli ukushayela izindlela eziningi ukuchumisa, okuyinto umthetho ingozi, kanye nezimoto. Nokho, nahlulele ukubukeka ezinye imiphumela emibi kungenzeka (kuhlanganise ukucobeka ukusabela, umbono yesikhashana esilufifi), kubalulekile ukwenza izenzo echazwe kahle.

Umuthi 'Aklasta ": Izibuyekezo nesineke

Njengomthetho, labo kakade wakwazi uqobo hlola umphumela izidakamizwa ngaphansi ukucatshangelwa, ukuveza imizwa yabo emihle kule yokwelapha. Le ndlela bayibiza ngokuthi i-izidakamizwa ngempumelelo. Indaba hhayi kuphela kule mpi ngokumelene kwamathambo futhi omuhle splicing amathambo, kodwa ngisho ngcono isimo e waphuka entanyeni femoral ezigulini esezikhulile. Futhi lokhu yi kusiza ukufeza akuzona zonke ejenti.

Nokho, azikho mihle kakhulu lesi sidakamizwa "Aklasta" kobufakazi nesineke. Imiphumela engemihle zenzeka kaningi. Phakathi kwazo kunabafundi ihlangabezane ngokuvamile kakhulu: imfiva, ukuqaqamba nobuhlungu bemisipha namathambo, Ukugodola. Nokho, iziguli ngokuqiniseka ukuthi kungakhathaliseki ukuthi, ukusebenzisa izidakamizwa ngaphansi ukucatshangelwa kuyadingeka. Kuyokusiza ukuba ukuxazulula eziningi izinkinga ezinkulu uhlelo zemisipha. Ngokuvamile, umuthi "Aklasta" iziguli ukushiya izibuyekezo omuhle.

analogs

Nokho Original ejenti Swiss kuba nomphumela omuhle enethambo, nokubaluleka kwalo oluhambisana umphumela wawo. Ngakho-ke, akubona bonke nesineke, ngeshwa, kungaba ukukhokhela ukwelashwa nge izidakamizwa ngaphansi ukucatshangelwa. Ngenxa yalokho, abantu abaningi bakhetha ezifanele Ukwakheka amalungiselelo "Aklasta" nozakwabo. Izibuyekezo ukwaba eziningi esikhundleni izidakamizwa. Phakathi kwabo - "Belklasta", "Zometa", "Rezorba" futhi "Rezoklastin FS". Iningi lawo abantu ngaphansi engabangela nemiphumela ebuhlungu, njengoba kubika emuthini "Aklasta" kobufakazi nesineke. Imiphumela engemihle uma kusetshenziselwa zenzeka kude kancane njalo. Khetha engazweli esikhundleni kungaba udokotela kuphela, self-enquma kungaholela ukuwohloka.

izimo isitoreji

Yeka ukuthi kungadabukisa kanjani ukugcina izidakamizwa "Aklasta"? Yokusetshenziswa, izilinganiso Kunconywa aqukethe izidakamizwa esebenzayo endaweni lapho izinga lokushisa ingeqi degrees amabili nanhlanu. Uma wavula umfuma lingalondolozwa esiqandisini akukho ngaphezu kwamahora amabili nane. Zonke lezi izinyathelo ezidingekayo ukuqinisekisa ukuthi imithi yayiphumelela.

ukuphila eshalofini

Ngakho-ke, esikhathini esithile ngemva ukukhiqizwa, ungasebenzisa izidakamizwa "Aklasta"? Izibuyekezo kanye nochwepheshe musa batusa ukusetshenziswa kwezimali emva kweminyaka emithathu kusukela ngosuku ukukhiqizwa. Emva kwalesi sikhathi, imithi ilahlekelwa impahla yayo futhi kuzuzise kungabangela abanye umonakalo empilweni yesiguli.

isiphetho

Izidakamizwa "Aklasta" - isidakamizwa ngempumelelo, okuyinto kakhulu ekudambiseni isimo leziguli izinkinga ezibangwa ukwehla kwamathambo. Isetshenziselwa isifo Paget sika, nokuvimbela waphuka yansukuzonke, kanye ulwe kwamathambo of genesis ahlukahlukene. Kubalulekile ukuthi ukusetshenziswa kwezidakamizwa Uchwepheshe abanekhono kuphela. Izici kwesicelo salo yokuthi ukwethulwa inqubo lokufeza can somNyango wezeMpilo futhi kuphela. Lokhu, phakathi kwezinye izinto, kunciphisa ingozi nesineke self-ukwelashwa. Kubaluleke ngokukhethekile ukuba acabangele leli phuzu, ikhumbula elingakanani nemiphumela eyingozi kakhulu enqabayo kungenzeka ngenxa isicelo okungafanele lokhu izidakamizwa. Kumele ulandele ngokucophelela zonke izincomo udokotela wakho, uyobanakekela ukuziphatha yokwelapha. Thola kabanzi mayelana izidakamizwa "Aklasta" (yokusetshenziswa, ukubuyekezwa). Imijovo kwezimali kuleli cala hhayi nje kuphela ingabe ukulimaza, kodwa futhi ulethe izinzuzo kulindeleke.

Qaphela lapho ekhetha indlela efanele ukwelashwa. Ungabi lazy ukuchitha isikhathi esithile ngaphandle ukuhlola ulwazi mayelana nalo. Lokhu kuzokusiza ukhethe izidakamizwa ezekhethelo kuwe kakhulu ukuthuthukisa impilo yazo.

Zinakekele futhi obathandayo. Khetha izinga. Futhi njalo uphilile!