Isidakamizwa esithi "i-Barol 20": imiyalo yokusetshenziswa, incazelo, ukwakheka nokubuyekezwa

Abantu banamuhla bahlupheka ngokuphindaphindiwe ngezifo ezihlukahlukene zegciwane lokugaya. Lokhu kungenxa yokudla okungenamsoco kuphela, kodwa nakwezinga lokudla okudliwayo, indlela yokuphila yokuhlala, kanye nokuphila okungcolile nokudla kwazo zonke izinhlobo zemithi.

Isilonda esiswini noma isifo sangasese ngeke kusimangaze muntu namuhla. Ngaphezu kwalokho, izifo ezinjalo zenzeka hhayi kuphela kubantu abadala nasebekhulile, kodwa nasezintweni ezincane. Yingakho izinkampani eziningi zokwelapha zikhiqiza izidakamizwa ezihlukahlukene ezisiza ukubuyisela i-mucosa yesisu bese kulungiswa umgudu wokugaya.

Ngokuvamile ukuphatha izimo ezinjalo iziguli zibekwe umuthi "i-Barol". Imfundo, ukwakheka, ukusetshenziswa kwalolu mithi kuzochazwa ngezansi.

Ukwakhiwa, ukupakisha, incazelo kanye nendlela yokukhululwa

Ngumaphi amafomu akhiqizwa umuthi onjenge- "Barol"? Isichasiselo, umbiko ubika ukuthi isidakamizwa esicatshangelwayo siqhubeka sithengiswa ngendlela yamacsules amhlophe namabhakabhaka, ahlanganiswe ngamabhaltri namaphakethe wephepha elinzima, ngokulandelana.

Isithako esisebenzayo sale mithi i-rabeprazole sodium. I-NPS, i-talc, i-hypromellose, i-sodium hydrogide, i- magnesium carbonate, i- macrogol, i-titanium dioxide, i-copolymer i-methacrylic acid, kanye ne-red and black iron oxides namanzi ahlanzekile asetshenziswa njengezingxenye ezengeziwe.

Izici zezemvelo

Isidakamizwa esithi "i-Barol 20" (amakhisolula) asebenza kanjani? Imfundo, incazelo yomuthi ikhombisa ukuthi lesi sidakamizwa sinemiphumela ye-antisecretory ne-antiulcer.

Ngokusho kochwepheshe, le mithi yisidakamizwa se-class antioxidant engabonakali isenzo se-anticholinergic. Ngaphezu kwalokho, akanalo izakhiwo ze-H2 histamine receptor antagonists. Kumele kuqashelwe ukuthi "i-Barol" (intengo, ukubuyekezwa komthengi kuzonikezwa ngezansi) kuphazamisa ukuvimba kwesisu. Ngenxa yalokho, isisu esiswini se-H + ne-K + adenosine triphosphatases, esisebusweni obungasese samaseli we-parietal, sithintekile.

Phakathi kwezinye izinto, izidakamizwa ezibuzwayo ziyi-inhibitor yepompo ye-proton yesisu.

Isenzo salesi se-ejenti siphumela ekuvinjeni kwesigaba sokugcina se-asidi yokuvimba. Ngemuva kokuthatha ama-capsules, aqoqwe futhi ahlanjululwe, futhi aguqulwe abe sulfenamide esebenzayo.

Umthelela we-antisecretory walesi sidakamizwa kwenzeka ngemva kwemizuzu engama-60 emva kokuphathwa komlomo. Kumele kuqashelwe ukuthi ukuthatha umthamo wokuqala wemithi kuholela emthethweni wokuvimbela okulinganiselwe.

AmaKinetics omuthi

Iziphi izakhi ze-kinetic ezitholakala kuma-capsules "Barol"? Imfundo kanye nencazelo yombiko wezidakamizwa ukuthi lo muthi ubonakala nge-bioavailability elingana no-50%.

Ukusetshenziswa kokudla, ikakhulukazi amafutha, kubambezela ukuxiliswa kwesithako esisebenzayo ngokwesilinganiso ngamahora amane. Noma kunjalo, leli qiniso alikho umthelela omkhulu emthonjeni walo wokwelapha.

Ukuxhumana kwezidakamizwa ezinamaprotheni e-plasma ngu-96%. Esikhathini sokudalwa kwamathambo, izingxenye ezifana ne-sulfone ne-thioether zakhiwa. Unomphumela obalulekile we-antisecretory.

Ukuhoxiswa kwezidakamizwa kwenzeka ikakhulukazi ngezinso.

Izinkomba

Iziphi izifo eziphatha ngokuphumelelayo lesi sidakamizwa "i-Barol 20"? Imiyalo yokusetshenziswa (intengo yalesi mithi ayikho kakhulu) ibonisa ukuthi le remedy ibonakala kahle lapho:

• Isifo se-Reflux gastroesophageal;
• Isilonda se-12-colon nesisu;
• I-Zollinger-Ellison syndrome.

Kumele kuqashelwe ukuthi le mithi ivame ukushiwo ukuqeda uHelikobakter Pilori ngokuhlanganiswa nama-antibacterial agents.

Ukungafani

Zikhona yini ukuphikisana nomuthi "Barol 20"? Imfundo yokusetshenziswa ikwazisa ukuthi kungenjalo kufanele kube khona amakhisolula anjalo lapho:

• Ukukhulelwa;
• Ukuziphendulela komuthi kumuthi;
• Ngaphansi kweminyaka engu-15;
• Ukuncelisa.

Isidakamizwa "i-Barol 20": imiyalo yokusetshenziswa

Ama-analog weleli thuluzi azokwethula ekugcineni kwalesi sihloko.

Ngokomyalelo, ama-capsules akhulunywa ngawo ahloselwe ukuphathwa ngomlomo. Ngokuhlukumeza okuhlukahlukene, kuthathwa ngesikhathi esisodwa. Isikhathi sokwelashwa sinqunywa udokotela kuphela.

Ngaphambi kokuba isifo se-reflux se-gastroesophageal, lesi sidakamizwa sisetshenziselwa i-capsule eyodwa amaviki angu-4-8. Uma kungekho ukuthuthukiswa, khona-ke ukwelapha kabusha kungenzeka.

Njengokwelashwa kwesondlo, umthamo wansuku zonke walesi sidakamizwa ngu-10-20 mg.

Ngemithi yokwelashwa ephawulekayo inqunywe ngesamba sika 10 mg kanye ngosuku amaviki amane.

Ukuze ukwelashwa kwe-Zollinger-Ellison syndrome, "i-Barol 20" inconywa ukuba ithathe isilinganiso esilingana no-60 mg (isilinganiso sokuqala nsuku zonke). Ngokwengqondo kadokotela, inani elibonisiwe lezidakamizwa lihlukaniswe ngamanani amabili.

Umthamo wansuku zonke wemithi yokwelashwa kwesilonda se-12-colon ngu-20 mg. Kulesi simo, isidakamizwa kufanele sithathwe inyanga.

Ngokuvamile, le mithi iphathwa ngaphakathi konyaka. Kulesi simo, isilinganiso esiphezulu esisodwa somuthi akufanele sidlule 60-120 mg ngosuku.

Izenzakalo ezimbi

Imiphi imiphumela emibi eyenziwa ngumuthi othi "i-Barol 20"? Imiyalo yokusetshenziswa ibonisa ukuthi lesi sidakamizwa sivame ukubangela imiphumela engathandeki njengezinhlungu zesisu, isisulu sokuqhwabanisa, ukuqothulwa, ukuhlanza, isifo sohudo, i-flatulence, i-dyspepsia nomzwelo womile emlonyeni.

Ngezinye izikhathi, uma uthatha imithi, isiguli sinenhloko, i-asthenia, isizungu, izinhlanzi, izinkinga zokulala, ukucindezeleka kokuphefumula, izinguquko ekushiseni komzimba, ukuhlukumeza esikhumbeni, njalo njalo.

Izimpawu zokudlula ngokweqile

Ziyini izimpawu zokudlula ngokweqile kwe-Barol 20? Imfundo yokusetshenziswa ithi ayikho amacala anjalo okwenzekile. Kodwa-ke, ochwepheshe abafaki ukuthi kungenzeka ukwandisa ukusabela okubi.

Kulesi simo, ukwelashwa kwenziwa ngendlela yokugcoba esiswini.

Ukuxhumana neminye imithi

Ngimaphi amalungiselelo okuvunyelwe ukuhlanganisa amaphilisi "iBarol 20"? Imiyalo yokusetshenziswa yazisa ukuthi i-rabeprozol inganciphisa kakhulu ukufihla kwe-hydrochloric acid. Lokhu kuthinta imingcele ye-kinetic yezidakamizwa, ukumuncwa okuxhomeke ngokuqondile ku-acidity yejuji yesisu.

Kwafunyanwa futhi ukuthi imithi ebuzwayo iyanciphisa ukuhlushwa egazini le "Ketoconazole" futhi yandisa okuqukethwe "kwe-Digoxin". Ngokuphathelene nalokhu, ukuphathwa okwamanje kanye nalezi zidakamizwa kudinga ukulawulwa okukhethekile ngodokotela oya khona (uma kunesidingo, khona-ke ukulungiswa kwesilinganiso kwenziwa).

Ngokuvamile, izidakamizwa ezibuzwayo zibhekene nokuxhumana okuncane nezinye izidakamizwa.

Izincomo Ezikhethekile

Ngaphambi kokuqokwa kwesidakamizwa esithi "Barol" yokwelashwa kwezifo ezihlukahlukene zesigcawu somzimba, kuyadingeka ukuba uhlole ukuhlolwa kwezempilo ukuze ugweme ukutholakala kwesifo esingokwemvelo. Lokhu kungenxa yokuthi ukuthatha le mithi kungafihla izimpawu zesifo esibucayi.

Imithi ebuzwayo ayinqunyelwe ngesikhathi sokuncelisa, ngoba ayikho ulwazi mayelana nokungena kwento yayo esebenzayo ebisi lomama.

Ngezifo ezinzima emsebenzini wezinso nesibindi, kudingeka imithi eqaphele.

Isidakamizwa esithi "i-Barol" asithinti kabi ikhono lesiguli lokushayela izimoto noma ukusebenza nezinye izindlela eziyingozi.

Uma kukhona izinguquko esikhumbeni, imithi kufanele imiswe.

Isitoreji, impilo yeshefu futhi ushiye ema-pharmacy

Isidakamizwa esithi "Barol" sikhishwe kuma-pharmacy ngaphandle kokudokotela kadokotela. Nokho, ukuyisebenzisa ngaphandle kokubonisana nodokotela kudikibala kakhulu. Uma kungenjalo, kungenza kube nzima isimo sesiguli esivele sinzima.

Iqukethe le mithi mhlawumbe ebumnyameni, engatholakali kubantwana nendawo eyomile, lapho izinga lokushisa lomoya lingadluli ama-26 degrees. Ukuphila kwe-shelf ye-capsules iminyaka emibili kusukela ngosuku lokukhiqizwa. Ekupheleni kwalesi sikhathi, ukusetshenziswa kwemithi kuvinjelwe.

Izindleko kanye namalungiselelo afanayo

Intengo ye-antiulcer cishe ngama-ruble angu-215. Uma kudingekile, kungashintshwa omunye wemithi enjalo njengeVeloz, Rabimak, Pariet, Rabelok, Rabeprazol, noRabizol. Isixazululo esinqunyiwe kufanele sinikezwe kuphela udokotela onolwazi, esekelwe ekuhlaziyweni kanye nedatha yokuhlolwa kwezokwelapha.

Impendulo evela kubathengi kanye nodokotela

Manje uyazi izindawo kanye nezici zomuthi "Barol 20". Imfundo kanye nezifaniso zokulungiswa nazo zinikezwe ngenhla.

Ukubuyekeza mayelana nale thuluzi kungatholakali kuhlukile. Iningi leziguli liqinisekisa ukusebenza kwalo okuphezulu.

Ochwepheshe baye bathola ukuthi izidakamizwa eziningi ezakhiwe ngesisekelo se-rabeprazole, isenzo sesici sisheshayo. Kulesi simo, asikho isidingo sokusebenzisa imithi ephakeme yomuthi noma ukwandisa imvamisa yokusetshenziswa kwayo.

Kumele kuqashelwe ukuthi isidakamizwa esithi "Barol" sinokubekezelelana okuhle. Iphelisa ngempumelelo ukuvalwa kwe-hydrochloric acid.

Imithi ebucayi ingahle ibekwe cishe noma yikuphi ukuphulwa okuyizinkomba zokusetshenziswa kwayo. Isibonelo, kusiza kahle ngesikhathi sokwelashwa kwe-reflux. Kodwa-ke, ezinye iziguli zithi ezinye izidakamizwa zesenzo esifanayo azizange zizisize ngaso sonke isikhathi.

Ngokuhlanganiswa nama-antibiotic agents, ama-capsules anjalo ngokuvamile avunyelwe ukwelashwa kwesilonda se-peptic. Lokhu kunikeza imiphumela emihle kakhulu.

Abantu abaningi abanomuzwa wokuthi "ukwanda kwe-acidity" baqala ukuzikhethela ngokuzimela izidakamizwa ezihlukahlukene zokwelapha. Ngokuvamile lezi zinhloso zisebenzisa ama-capsules "Barol". Abanye abathengi bathi leli remedy liye lathuthukisa kakhulu isimo sabo. Nakuba akuzange kusize ezinye iziguli. Ochwepheshe bathi isizathu sokungasebenzi kahle kwale mithi kuwukuthi ukuphazamiseka okukhulunywe ngenhla kuhlotshaniswa nezinye izinto ezingavamile emsebenzini wendlela yokugaya ukudla, okudinga ukwelashwa okufanele. Ngakho-ke, kubaluleke kakhulu ukuxhumana nodokotela ngendlela efanele ngesikhathi, emva kokuhlolwa kwezokwelapha, okuzokunikeza ukuxilongwa okunembile nokubeka ukwelashwa okufanele.