"Fenilin": yokusetshenziswa, analogs, ukubuyekezwa

Yini abantu bethi mayelana nokulungiselela ezifana "Fenilin"? Uphenyo kodokotela kanye neziguli zizohlolwa ekupheleni isihloko. Siphinde ngikuxoxele kuzinjongo ke ezinqunyiwe ikhambi, ukwamukela kahle, uma unalo yini imiphumela emibi, kanye contraindications nozakwabo.

Ukwakheka kanye ukuma

Ngayiphi ifomu senziwa imithi "Fenilin"? Iziyalezo imibiko ukusetshenziswa ukuthi lokhu izidakamizwa itholakala amaphilisi, ketshezi asebenzayo okuyinto phenindione. Njengoba izingxenye asizayo wasebenzisa i-lactose, isitashi, citric acid kanye talc.

pharmacodynamics

Iziphi izici ine izidakamizwa kwemithi "Fenilin"? Iziyalezo yokusetshenziswa uthi izidakamizwa liyithinta ngokuqondile ku igazi ekunqandeni. Kuyinto anticoagulant engaqondile senzo.

Ukuthola nomuthi ikhuthaza nesenzakalo hypoprothrombinemia, okuyinto ngenxa yokwephula kwetinhlavu prothrombin esibindini. Lokhu kusho futhi kakhulu kunciphisa kumiswa isici 7, 9 no 10. Kulesi simo, it kunethonya elikhulu cumulated kuqhathaniswa ne neodikumarinom.

Ukulandela ekuphathweni temlomo, amaphilisi lokuhlushwa incipha igazi ekunqandeni izici amahora 8-10. Umthelela maximal zomuthi waphawula ngemuva kwamahora 25-30.

Pharmacokinetics

It is angena letindzala kwegazi izidakamizwa "Fenilin"? ochwepheshe lezivakashi bathi kule izidakamizwa elinesimo ukumuncwa ephelele futhi ngokwanele okusheshayo. isithako zayo asebenzayo lingena isithiyo histo-hematic bese buthelela ezicutshini.

Umuthi is akheka esibindini nezinso isuselwe (njengoba metabolites futhi angashintshiwe).

Izinkomba ukusetshenziswa

Iyini injongo okunqunyiwe "Fenilin" ithebhulethi? Izibuyekezo ochwepheshe ukubika ukuthi lokhu izidakamizwa isetshenziselwa ngokwelashwa nokuvimbela. I izinkomba esiyinhloko ukwamukelwa kukhona thrombosis, thrombophlebitis, ukuxakeka thromboembolic kubangelwa unhlangothi embolic futhi isilethikusebenza, kanye ukwephulwa okufanayo.

Ngaphezu kwalokho, imithi yokubika evame ukunikezwa nokuvimbela thrombosis ngemva kokuhlinzwa.

Izimo

Kungaphansi kwaziphi izimo isiguli asivunyelwe ukuthatha izidakamizwa "Fenilin"? Yokusetshenziswa ngokuvumelana Izimo ezilandelayo:

• ukushayisana nezinso isibindi;
• ezingeni kokuqala prothrombin 70%;
• anda permeability semithambo;
• oluhambisana diathesis nezinye izifo ezihambisana ne nokuncipha igazi ekunqandeni;
• izifo emathunjini ipheshana wokugaya ukudla;
• neoplasms abulalayo;
• pericarditis.

Asinakusho edingida izidakamizwa is hhayi Kunconywa ukusetshenziswa ekuqaleni yokukhulelwa ezinsukwini ezimbalwa ngemva kokubeletha kanye esesikhathini.

Izidakamizwa "Fenilin": yokusetshenziswa

Okubukwe ukusetshenziswa nomuthi kuphela abaphathi ngomlomo. lwemithi zayo zokwelapha inezici ezithile, ngokuqondene ukusetshenziswa le imithi kufanele kube kuphela kuma-oda kadokotela.

kokuqala umthamo wansuku zonke ngokuvamile 0,11-0,17 g (4 umthamo owodwa). Ngakusasa, inani izidakamizwa kuyehla kube 0,08-0,14 g, futhi eminye ukuze 0.02-0.05 Ngemva kwalokho, umthamo amaphilisi luncike ezingeni prothrombin egazini.

Inani eliphelele izidakamizwa ngesikhathi kufanele kube 0.05 g futhi nsuku zonke - mayelana 0.2 amagremu

Ngokuba nokuvimbela yezinkinga thromboembolic kuyadingeka ukuthatha 0.03 g zomuthi ngelanga sokuhlukanisa umthamo ngesigamu.

Ukwelashwa of thrombosis acute idinga ukwengeza eyamukelayo heparin. Lokhu kudinga ukuqapha esiqinile udokotela, kanye ngesifundo esihleliwe lemali okuphoqelekile okwenziwa ezikhungweni prothrombin egazini nezinye izinto e ekunqandeni yayo.

Ukwelashwa nge "Fenilin", analogue zazo sizobe uhlu olungezansi, ayeke kancane kancane.

side effects

Ingabe imiphumela emibi umuthi "Fenilin"? Indlela yokusebenzisa kanye umthamo we izidakamizwa kumele ngokuqinile waphawula. Lena ngokuyinhloko ngenxa yokuthi ngesikhathi yokwelapha, isiguli bangezwa ezihlukahlukene komzimba nezinto ezifana nohudo, ukucanuzela kwenhliziyo kanye ne-hepatitis. Futhi, ngokuvumelana kodokotela kanye neziguli, ezimweni ezingajwayelekile, kukhona ubuhlungu bekhanda, imfiva, ushintsho ngombala umchamo kanye nezinkinga zesikhumba nge hematopoiesis.

Izimpawu ukweqisa izidakamizwa

Endabeni ka ukweqisa izidakamizwa, iziguli zingase zibe zimbi izimpawu zazo emibi. Njengoba ekwelapheni izimo ezinjalo kudinga ukususwa esiyisibopho izidakamizwa, kanye ngokushesha abaphathi esicutshini "menadione" aphoyintimenti rutin namavithamini noma cha P, chloride, ascorbic acid, i-calcium ne ubambe yokwelapha jikelele lingaze.

Izidakamizwa ukuxhumana "Fenilin" ukulungiselela

Kusukela lokho ezinqunyiwe iyindlela thina okuxoxwe ngawo ngenhla. Ake sibheke ukwaziswa okwengeziwe.

Lapho kuhlangene kubhekwe izidakamizwa "Heparin", salicylates, "Qi-metidinom" futhi sulfonamides angaba namandla nethonya lazo anticoagulant. Ngakho ukwandisa nekusebenta "fenilina" can anabolics, "allopurinol", "Azathioprine" analgesics isidakamizwa "Amiodarone", tricyclic antidepressant, imithi elwa namagciwane, gluco-corticosteroids, androgens, "Diazoxide," "Dizopiramid" "INH", " Phenylbutazone, "" metronidazole "," Klofib-rat "," Alpha-tocopherol "," reserpine "," quinidine "" paracetamol "," Disulfiram "," Cyclophosphamide ", futhi ama-hormone.

Ngokuphawulekayo attenuate isenzo phenindione kukhona vitamin K "propranolol", ascorbic acid, kusho umchamo alkalizing "rifampicin" antacids "phenazone", "Haloperidol", barbiturates inzalo temlomo, isisu, "meprotan", "Carbamazepine" futhi " cholestyramine. "

izincomo ezithile

C ngokuqapha ukuthi izidakamizwa ezinqunyiwe ukuze iziguli esezikhulile nabantu embolism yamaphaphu, isibindi nezinso isifo, erosive nezifo esidalwa yizilonda emathunjini sibe yokusetshenziswa pheshana emathunjini, esikhathini kwangemva kokubeletha, futhi pericarditis.

Ukwelashwa "fenilina" kufanele kube ngaphansi kweso olukhethekile udokotela ngesifundo saziso ehlelekile kwegazi inani prothrombin nezinye izinto coagulation. Futhi ubambe jikelele umchamo zokuhlolelwa kusenesikhathi hematuria.

Kwezinye iziguli, edonsa izidakamizwa kungabonakala nasemkhakheni umchamo staining pink nezintende zezandla - owolintshi. Lokhu kungenxa umzimba phenindione.

Izidakamizwa "Fenilin": nozakwabo kanye nezindleko

The main ukucabangela analogue ejenti yizidakamizwa ezifana "Varfapeks" "Marevan", "neodikumarina" et al.

Thenga imithi "Fenilin" Izibhebhe 20 kungabangwa ruble 120-140.

Ukubuyekeza ku imithi

Kungakhathaliseki imithi ethile kuyaphumelela "Fenilin"? Nobufakazi ngalokhu izidakamizwa zahlukahlukene kakhulu. Ngokusho kwemibiko yabo, leli thuluzi ingenye imikhiqizo ephumelela kakhulu ezisiza ukuthuthukisa isimo igazi.

Ngenxa yokwelashwa ka coagulation imingcele ekutheni iziguli eziningi ukubuyela esimweni esivamile. Kufanele kuphawulwe ukuthi nje ngesonto ngemuva kokuqala ukwelashwa isiguli waphawula ubungcono isimo jikelele. Lokhu kungabi sengxenyeni imilenze ndikindiki, amajaqamba indoda ukuthi angiyeke ukukhathazeka.

Njengoba umkhuba ubonisa, kwezinye iziguli ngesikhathi ephethe izibhebhe "Fenilin" umongozima njalo. Nokho, ngokusho kodokotela, ushintsho olunjalo kuyinsakavukela. Ngemva imithi oyinikiwe, zonke ejwayelekile.

Ngaphandle kokuxoxa ukuphumelela izidakamizwa, inganqotshwa futhi izindaba iziguli ukuthi lokhu izidakamizwa ngokuvamile counterfeited. Ngakho-ke, uma uthenga njalo kunengozi ukuthenga umuthi mbumbulu ezintsha. Ukuze ugweme sehlakalo, ukuthenga imithi kufanele kube Pharmacy omethembayo ukuthi ube izincomo ezinhle kuphela.