"Excedrin": nozakwabo. I ikhambi migraine "Excedrin": kuzibuyekezo, izintengo, analogs

Migraine - lena sifo, awakwazi ukudluliselwa ngaphandle analgesics. Ukuhlaselwa uyakwazi izinsuku 4. Umuntu okukhulunywa ngaye lapha isikhathi ilahlekelwa ikhono layo emsebenzini. Ngesikhathi esifanayo uyawasebenzisa imithi enamandla ukuqeda agony throbbing. Kodwa, ngeshwa, iningi amathuluzi ongaqeda ukungakhululeki ezinjalo, umlutha futhi kuholela yokuthi lesi sifo kuba amahlala khona. kwemithi Modern uye wazakhela izidakamizwa enkulu entsha. Kusho, kahle ukuqeda migraine, ukunciphisa ikhono ukusebenza, kodwa ayiluthi, umuthi "Excedrin". Analogs zomuthi akuyona ayisasebenzi.

Incazelo emfushane

I ikhambi migraine "Excedrin" kuyinto ukulungiselela kuhlanganiswe okuqondene iqembu analgesics-antipyretics. Isetshenziselwa zekhanda ezinamandla. Ngokuphumelelayo kusho "Excedrin" kusukela migraines. Kulokhu, kungavimbela ngisho kuhlasela.

Ukwakheka izidakamizwa

ukusebenza Umuthi itholakala izithako zako. Umuthi liqukethe:

• acetylsalicylic acid;
• caffeine;
• paracetamol.

Kuyinto ngenxa lezi zinto kunemiphumela ahlukahlukene emzimbeni. Ngenxa yalokho, yibhange ngokushesha, ubuhlungu iboshiwe ngokugcwele.

Paracetamol e isamba 250 mg, Acetylsalicylic acid - 250 mg, ne-caffeine - 65 mg iphilisi elilodwa liqukethe izidakamizwa "Excedrin". Ukwakheka ngaleyo ndlela lapha kusho izithako ezisebenzayo zibaluleke kakhulu. Kuyancomeka ukusebenzisa izidakamizwa ngokucophelela okukhulu. Iziguli kufanele acabangele umthamo kanye singadluli ke.

Ngaphezu kwalokho, lokhu izidakamizwa zihlanganisa izithako asizayo:

• giproloza;
• microcrystalline cellulose;
• stearic acid.

Imiphumela emzimbeni

Ezibhebheni migraine "Excedrin" esakhiwe ngezinto ezintathu ezahlukene ezithinta izakhiwo ezahlukene. inhlanganisela yabo ivumela ukuqeda ubuhlungu yanoma yiluphi uhlobo. Njengoba ukuhlaselwa migraine ephelezelwa ukungakhululeki ngokwanele eside futhi kanzima, balahle yona kumelwe imithi enamandla kakhulu. Lokho sinjalo izidakamizwa "Excedrin".

Yini leli thuluzi uye wabonisa ukukhinyabezeka kwayo futhi kuba namuphi umphumela? Impendulo yombuzo itholakala nomthelela emzimbeni ingxenye ngayinye eziqukethwe izidakamizwa:

1. Paracetamol. Ingqikithi has a izakhiwo aphakeme eqeda ukuvuvukala futhi antipyretic. It uyakwazi kuthinta isikhungo ubuchopho unesibopho ukulawula izinga lokushisa kule ngxenye. Indima ebalulekile nokuqedwa migraine it has izinga eqeda ukuvuvukala, ngoba imfiva ingeyona izimpawu ezikhungathekisayo zalesi sifo.
2. Acetylsalicylic acid. Uphiko kuyahluka evelele izakhiwo antipyretic. Uyakwazi ukubambezela nekugwema ukuvuvukala. Kulesi kunciphisa ubuhlungu. Acetylsalicylic acid olungavimba nesenzakalo amahlule. Eyeka inqubo kumiswa yabo emangqamuzaneni, ngokuphelele kuthuthukisa kwegazi igazi ezindaweni elikhanyayo.
3. Caffeine. Iqhaza yalolu ketshezi ukuze banciphise ubuhlungu izinto eziphawuleka kakhulu. Ama-aspirin futhi paracetamol ongaqeda okwesikhashana ukuqaleka. Caffeine kunomphumela omuhle kwegazi ebuchosheni futhi usiza ukuqeda izimbangela zezifo. Ngaphezu kwalokho, kukhuthaza zokuphefumula futhi izikhungo vasomotor, ikhuthaza ukunwetshwa imithambo yegazi ayisesemikhulu, kuvimbela platelet esibophezelayo. Caffeine kuyinto aqede kakhulu ukukhathala ukozela. It Ngokuphawulekayo kwandisa nekusebenta umzimba ithoni yayo, kanjalo impilo lesiguli jikelele. Inhlanganisela aspirin ngalolu ketshezi uyakwazi ekuthuthukiseni ukugeleza kwegazi futhi nakanjani kuthinte imithambo ingqondo.

Pathologies lapho ukulungiselela sisetshenziswa

Kungcono ukusebenzisa "Excedrin" amaphilisi ngenxa yobuhlungu syndromes okujula okuncane noma okusesilinganisweni Lokudabuka ezahlukene:

• migraine;
• ikhanda;
• neuralgia;
• amazinyo;
• myalgia, arthralgia (ukungakhululeki emalungeni nemisipha);
• algomenorrhea (ubuhlungu esesikhathini);
• syndrome okunomkhuhlane.

Pharmacokinetics

Ezimweni eziningi, umuthi emzimbeni "Excedrin" kunokwenzeka asibekezeleleki kahle. Izibuyekezo Umthengi uyaqinisekisa ngokugcwele lokhu. mphumela zomuthi liyadingeka bathole ezinye zezici zalo:

1. Paracetamol ngokuphelele ugxile pheshana emathunjini. It is akheka esibindini, izinso kanye excreted njengoba glucuronide futhi sulfate conjugates. Ngaphansi kuka-5% we kweminyango impahla ngendlela unmodified. Njengoba i-plasma amaprotheni sibopho iwubala uma usebenzisa umthamo ezivamile zokwelapha. Kodwa nge ukwanda yokugcina - liyakhuphuka. metabolite Hydroxylated kwakheka nengcosana esibindini bedle oxidases okuxubile futhi ngokuvamile neutralized ngu sesibopho ukuthobisa glutathione, bangathola amaphuzu nge ukweqisa izidakamizwa-paracetamol kanye kubangele ukulimala kwesibindi.
2. Acetylsalicylic acid is ngokuphelele futhi ngokushesha matasa. It is hydrolyzed ku wokugaya ukudla pheshana, igazi isibindi. Kuleli fomu salicylates. Ngaphezu kwalokho, kuthiwa akheka esibindini.
3. Caffeine nayo ngokushesha ugxile ngokugcwele. Ubuningi esiphezulu emzimbeni siyenzeka imizuzu 5-90 emva ukusetshenziswa kwezimali esiswini esingenalutho. Excretion kwenzeka ngenxa umzimba hepatic. Ingqikithi is basakaza phezu zonke uketshezi lomzimba. Ukuxhumana amaprotheni oketshezi olungenambala olusegazini-35%. Uphiko is akheka ngokuphelele futhi excreted ngu nezinso.

Umthamo lwemithi

Ifanele ekuphathweni temlomo kusho "Excedrin". Umuthi isetshenziswa ngesikhathi noma ngemuva kokudla. Kunconywa ukuba baphuze amanzi in inqwaba.

umthamo owodwa abadala nentsha (kusukela eminyakeni 15) - 1 ithebhulethi njalo 4-6 amahora. Uma umuntu enomuzwa izibonakaliso migraine esizohlasela, kutuswa ukusebenzisa ngesikhathi esisodwa 2 amaphilisi. Lokhu kuzovimbela ngokuhlasela ukugula. Nokho, umuntu kufanele akhumbule ukuthi kudle amayunithi ezingaphezu kuka-6 ngosuku akuvunyelwe nakancane.

isixwayiso esibaluleke

imithi Ngempumelelo avunyelwe isicelo ukungakhululeki ubuhlungu izinsuku 3. Phakathi nalesi sikhathi, isiguli kufanele bonana nodokotela wakho kuqala, abayoba ukhethe ephelele izindlela ehlukile ngazo ukulwa nalesi sifo.

Kwezinye izimo, isiguli Kunconywa ukunweba ukusetshenziswa kwezidakamizwa. Kodwa kungenzeka isinqumo esinjalo senziwe ngesisekelo izinkomba ezifanele kuphela onguchwepheshe. Yidla amaphilisi migraine "Excedrin" ngumnikazi izinsuku ezingaphezu kwezingu-3 is hhayi Kunconywa. Ukwandisa umthamo abangela nemiphumela emibi ngendlela efanayo. Ezinjalo njengoba ukulimala kwesibindi ngenxa ekuqongeleleni metabolites emzimbeni.

side effects

Ukusetshenziswa kwezidakamizwa akakwazi ngempela nethonya elihle emzimbeni. Njengoba enezinto eziningi side effects kusho "Excedrin". Izidakamizwa analogue kungase iphakamise ukwelapha udokotela, uma izidakamizwa oshiwo ngenhla is ezingafanelanga esigulini.

Ngakho, lokhu okulandelayo side effects:

• ukucanuzela kwenhliziyo, ukuhlanza,
• gastralgia;
• hepatotoxicity;
• izilonda erosive futhi esidalwa yizilonda emathunjini sibe emathunjini;
• nephrotoxicity;
• komzimba;
• okwandisa ingcindezi;
• tachycardia;
• isiyezi;
• bronchospasm;
• ikhanda;
• angaboni kahle;
• ehle platelet wokuhlanganisa ;
• tinnitus;
• oluhambisana syndrome (ukopha kwezinsini, epistaxis, purpura);
• ebulalayo erythema exudative (noma Stevens-Johnson syndrome);
• ubuthulu;
• enobuthi epidermal necrolysis (noma Lyell Syndrome);
• isifo sezinso (Amathuba necrosis papillary);
• ukuthuthukiswa ezinganeni Raynaud Syndrome (hyperpyrexia, lactic umzimba, iziyaluyalu isimiso sezinzwa futhi psyche, ukuhlanza, ukuqothuka kwezinwele okungavamile kuphelile isibindi umsebenzi).

Izimo kokuthola

Ngeshwa, imithi ngeke zizuzise kubo bonke abantu. Ngemva izindlela enezinto eziningi Izimo. Ziyaqiniseka ukuthi kucatshangelwe ngaphambi kokufaka isicelo. Kodwa yithemba uma imithi akwenzeki ngaphandle izindleko. Udokotela ukuba khona kulula kakhulu ukuba esikhundleni ithuluzi "Excedrin". Analogs uvumele ukufeza umphumela eyamukelekayo.

Imithi is contraindicated ku pathologies ezilandelayo nezimo:

• Hypersensitivity ukuze izithako;
• izilonda emathunjini esigabeni acute;
• isifuba somoya bronchial,
• ukopha emathunjini;
• yansukuzonke polyposis acinene (sinuses paranasal);
• ukungabekezelelani ukuba ama-NSAID;
• izinqubo kuhlinzwa ezihambisana ukopha;
• oluhambisana diathesis;
• nomfutho wegazi ophezulu;
• hemophilia;
• gipoprotrombinemii;
• nomfutho wegazi ophezulu portal;
• ukufiphala;
• ischemia okunzima inhliziyo;
• K beriberi;
• yokuntuleka zikashukela-6-phosphate dehydrogenase;
• ukwehluleka kwezinso;
• ukhulelwe;
• lactation;
• iziyaluyalu ubuthongo;
• ukucasuka;
• yobudala Wezingane (umuthi awusebenzi iminyaka engu-15).

ukweqisa izidakamizwa wezokwelapha

Medicine "Excedrin" migraine kumele kuthathwe ngemithamo kukhonjisiwe ngenhla. Njengoba ukuhlukumeza ejenti kungaholela izinkinga eziningi ezingezinhle.

Mayelana ukweqisa izidakamizwa-paracetamol zibonisa izici ezilandelayo:

1. Phakathi ngosuku lokuqala lapho ayilutho isikhumba, ukuhlanza, ukucanuzela kwenhliziyo, ubuhlungu besisu, kahle-glucose umzimba, ukudla, ukudla lactic umzimba.
2. Ngemva 12-48 amahora wokusebenza izimpawu kungenzeka yokwehluleka kwesibindi ukuwubeka Ukulandelana encephalopathy. Ukuze kakhulu ukweqisa izidakamizwa kungenzeka - ikhoma nokufa. Kungase kube ukwehluleka kwezinso, ephelezelwa necrosis ijabulise, pancreatitis, arrhythmia.

Overdose cuphuluza acetylsalicylic acid, has zimpawu ezilandelayo:

1. Izindaba Ezintsha - ukuhlanza, isicanucanu, isiyezi, angaboni kahle, tinnitus, ikhanda.
2. Ngo ubuthi ezinzima - iphika, cyanosis, dyspnea, okunamathelayo izithukuthuku ebandayo, lactic zokuphefumula, ukukhubazeka zokuphefumula.

Ukuhlukumeza kubangelwa caffeine uwukubonakaliswa zimpawu ezilandelayo:

• gastralgia;
• ukuyaluza, ukukhathazeka;
• ukudideka;
• ukungahlaliseki;
• amanzi emzimbeni;
• arrhythmia;
• ukuchama kaningi;
• tachycardia;
• komzimba;
• anda ubuhlungu kanye nokuzwela;
• eliqhaqhazelayo;
• enkeneneza ezindlebeni;
• ukucanuzela kwenhliziyo, ukuhlanza (kwesinye isikhathi khona igazi);
• zesifo sokuwa.

Uma ukweqisa izidakamizwa kufanele afune usizo lwezokwelapha oluphuthumayo. Phakathi neminyaka yokuqala 4 amahora kunconywa ukugeza esiswini, ntombazane ukuhlanza. Laxatives ziphele futhi lisho "carbon Kuvulwa".

analogue imithi

Khumbula ukuthi noma izidakamizwa kufanele udokotela, njengoba ejenti ngamunye has izinkomba zayo kanye contraindications.

Futhi kuphela udokotela uyakwazi bamelele omunye imithi izidakamizwa "Excedrin". Analogs esemazweni wamanje kanje:

• "Akvatsitramon".
• "Atsifein".
• "Askofen".
• "Kofitsil plus."
• "Tsitramarin".
• "Migrenol engaphezulu."
• "Tsitramon".
• "Tsitrapar".

Lokho okwakudingeka ukuze kukhokhwe izidakamizwa

Ukuze zonke ukusebenza kahle yayo, engabizi imithi izindleko kubathengi "Excedrin" kusukela migraines. Inani iphakethe (amaphilisi 10) luyehluka in the ububanzi ruble 120-150. Izindleko kulungiselelwa amaphilisi ruble 210-250 20.

Ukusebenzisana neminye imithi

Iziguli thatha izidakamizwa "Excedrin" Kumelwe kuqondwe ukuthi kungaba ngcono ukusebenza emzimbeni izindlela ezifana:

• "Heparin";
• anticoagulants engaqondile;
• "Reserpine";
• izidakamizwa hypoglycemic;
• hormone steroid.

Qaphela ukuthi ukusetshenziswa ngesikhathi esisodwa izimali "Excedrin" namanye ama-NSAID kungadala imiphumela emibi. Ngokwesibonelo, nokuxhumana ne protivopodagricakih izidakamizwa, izidakamizwa antihypertensive, kusho "Furosemide" kuholela kahle ongaphakeme ala maqembu izidakamizwa.

umbono umthengi

Noma yimuphi izidakamizwa has (iyathinteka nelaphe "Excedrin") izimpendulo, okuhle nokubi.

Abanye abathengi ukutshela ngokungagwegwesi ukuthi, njengoba beye bazama izidakamizwa kanye, ngeke ingxenye nabo. abesifazane abaningi buyindlela ephumelelayo esikhwameni sakhe. Ngeke wazi ukuthi uma kuhlaselwa ubuhlungu ngeke zikufice. Iziguli ezinjalo uqaphela ukuthi esinye isibhebhe sibonisa ihora uyakwazi ukuqeda izimpawu ezingezinhle. Futhi endabeni migraines ezinzima aqede ubuhlungu imithi amaphilisi 2 "Excedrin". Izimpendulo abonisa ukuthi ukusebenza kahle omuhle ithuluzi.

Okunye abathengi ubambe nombono ohlukile, bememezela lusizo izidakamizwa. Bathi izinto asebenzayo imithi angathengwa ngamunye kuba ishibhile kuka ekhemisi. Nokho, lezi amakhasimende ukhohlwe ukuthi ukuze sibe abafundisi abaphumelela izidakamizwa kwaba ngenxa inhlanganisela efanele zonke izingxenye ephelelisanayo kahle.