"Diza" (anti-njengemithi yokungezwani komzimba nokuthile amaphilisi): yokusetshenziswa, analogs, ukubuyekezwa

Indlela yokusebenzisa lesi sidakamizwa "Disa"? Iziyalezo uyalisebenzisa yini leli thuluzi izokwethulwa ngezansi. Uyofunda ukuthi izingxenye zifakwe wathi ifomu izidakamizwa lapho itholakala, ukuthi kungenzeka ukuba linqume ke izingane nabesifazane abakhulelwe.

Ukwakheka, ukuma, incazelo nomuthi

Yini izingxenye kuhlanganisa izidakamizwa "Disa"? amaphilisi Anti-njengemithi yokungezwani komzimba nokuthile, imfundo okuyinto linamathele ibhokisi okwesibhakabhaka, we-lenticular wangakwesokunxele futhi isiyingi isesimweni, kanye umbhalo «LT» ngakolunye uhlangothi. Isithako asebenzayo we umuthi desloratadine. Futhi-ke yakhiwa izithako engeziwe njengoba mannitol microcrystalline cellulose, pregelatinized corn isitashi, magnesium stearate futhi talc.

Ngokuqondene enamathela ifilimu amaphilisi, bahlanganisa blue Opadry, macrogol futhi indigo udayi.

Kufanele futhi wazi ukuthi izidakamizwa kubhekwe akhiqizwa uhlobo isiraphu. isithako zayo asebenzayo futhi izenzo desloratadine.

kwemithi

Kanjani lesi sidakamizwa "Disa" (anti-njengemithi yokungezwani komzimba nokuthile amaphilisi)? Regulations yayilokhu izidlela nje kule ndawo, kusho ukuthi-ke kuyindlela antihistamine eside esebenza. Kuyinto blocker histamine neuropathy H1-yokwamukela.

Isithako asebenzayo we nomuthi kuyinto metabolite eyinhloko esebenzayo ye loratadine. It kuvimbela ukusabela iguliswa, ukukhulula cytokines proinflammatory futhi chemokines. Futhi, lesi sici kunciphisa ukukhiqizwa superoxide anions, chemotaxis futhi adhesion eosinophils.

kuzichaya izidakamizwa kuyasiza ekuvimbeleni ukuthuthukiswa kanye nokwenza lula komzimba. ukulungiselela Okubukwe has protivoekssudativnoe futhi antipruritic izakhiwo, kuvimbela zibe of imisipha abushelelezi, edema kwezicubu futhi kunciphisa permeability ka-capillary.

Tablets "Sprinkler", intengo ezizoboniswa ngezansi, ke akunamthelela le CNS, kodwa futhi kuba nomphumela okulalisayo (ngamanye amazwi, akakubangeli ukozela) futhi akunamthelela lengqondo isimo sabantu (lapho ithola umthamo Kunconywa). Ngaphezu kwalokho, izidakamizwa okukhulunywa akavele QT kweminyaka electrocardiogram.

Umthelela zokwelapha zomuthi iqala ngaphakathi ihora ngemva kokungenisa, futhi ihlala usuku lonke.

Pharmacokinetics

Yini izidakamizwa pharmacokinetic has "Disa" (anti-njengemithi yokungezwani komzimba nokuthile amaphilisi)? Umhlahlandlela ubika ukuthi ngemva ngokuthatha izidakamizwa izidakamizwa esebenzayo it is kahle ugxile kusukela pheshana emathunjini. Ngo-plasma kunqunywa ngesigamu sehora, futhi okuhlushwa wobuningi kufinyelelwe ngemva kwama-iri amathathu.

Ukuxhumana ne ukulungiswa plasma amaprotheni 85-87% nokuqeda isigamu-nokuphila - amahora angaba ngu-28. desloratadine excreted kuyinto okukhipha ngokusebenzisa emathunjini (ngaphansi kuka-7%) kanye umchamo (ngaphansi kwama-2%).

izinkomba

Kusukela yokungezwani komzimba izidakamizwa ebusweni kuyasiza kahle. Isetshenziselwa hhayi kuphela ukuba lula, kodwa futhi ukuqeda lezi zimpawu ezilandelayo:

• isifuba (ukuqubuka noma ukuluma);
• rhinitis nomzimba (amakhala yisisu, sneezing, ukulunywa ka ulwanga, ukuminyana acinene, ububomvu namehlo silume, ekhaleni silume, amehlo zamanzi).

Izimo

Kusukela komzimba ngesikhathi sokukhulelwa izidakamizwa "Disa" akumele zisetshenziswe. Futhi, aluboniswa ngesikhathi ibele futhi izingane ezingaphansi kweminyaka engu-12 ubudala (ukuphepha nokusebenza ngempumelelo ungazange sezisunguliwe). Musa ukusebenzisa lolu nomuthi futhi ngezinye ezwela oluphakeme isiguli ekhona noma iyiphi izithako okungeziwe nomuthi.

Ngokucophelela okukhulu "Disa" iphilisi ezinqunyiwe ezinzima esingamahlalakhona kwezinso.

Izidakamizwa "Disa" (anti-njengemithi yokungezwani komzimba nokuthile amaphilisi): Imiyalelo

Linqume amaphilisi ezinjalo kufanele kuphela onguchwepheshe emincane. Yokungezwani komzimba (urticaria, pruritus, ukuqubuka, njll) e izingane ezineminyaka engu-12 kanye nabantu abadala ngokufanayo iqedwe. Ngokusho imiyalelo, ithebhulethi kumele kuthathwe ngomlomo, kungakhathaliseki ukudla. Umthamo zomuthi kunqunywa udokotela futhi ngokuvamile kuba 5 mg kanye ngelanga (isb 1 ithebhulethi ngelanga).

ukusabela ezingezinhle

Allergy izingane eminyakeni engaphezu kwengu-12 ukulungiselela "Disa" kufanele sinikezwe ngokucophelela okukhulu. Lokhu kungenxa yokuthi lokhu izidakamizwa kungabangela inqwaba engemihle.

Ngokuvamile, iziguli ukusabela ezingezinhle ezifana ukukhathala, ukuphathwa ikhanda ezingamahlalakhona, kome umlomo.

Phakathi kokuma tiphindze ezikhonjwe nezinye imiphumela emibi. Sethula manje:

• Kusukela isimiso sezinzwa bangezwa ukozela, lengqondo hyperactivity, isiyezi, nokuqwasha.
• On the ingxenye ipheshana wokugaya ukudla kukhona ubuhlungu besisu nohudo, ukucanuzela kwenhliziyo, dyspepsia, nokuhlanza.
• Kusukela leli pheshana biliary futhi isibindi zenzeka ezinjengokungcoliswa ukwanda lokuhlushwa bilirubin, ama-enzyme isibindi iyokhushulwa, kwesibindi.
• Senhliziyo kanye neziguli semithambo ayinandaba tachycardia futhi palpitations.
• On the ingxenye amathambo kwemisipha uhlelo waphawula myalgia.

Kufanele kuphawulwe ukuthi uma uthatha kokucubungula izidakamizwa iziguli zingase zibhekane nokuphazamiseka engqondweni njengoba ukusangana nokungezwani komzimba nezinto ezifana ukulunywa, anaphylaxis, amawala, urticaria futhi angioedema.

Izimpawu ukweqisa izidakamizwa

Allergy izingane eminyakeni engaphezu kwengu-12 kanye nabantu abadala izidakamizwa "Disa" Kumele kuthathwe ngemithamo Kunconywa udokotela.

Ngemva kokuthola lezi izidakamizwa ebulilini (isibonelo, izikhathi 9, okuyinto ilingana 45 mg) Akazange abute izimpawu emtholampilo abalulekile. Kodwa kungenzeka ukuthuthukisa ukozela.

Njengoba ukwelashwa liyadingeka iphume esiswini futhi wenze namalahle. Kufanele kuphawulwe ukuthi desloratadine kuyinto okuphumayo by hemodialysis.

Ukuhambelana nezinye izidakamizwa

Ukuxhumana "Disa" izidakamizwa nezinye izidakamizwa sezihlonziwe (kuhlanganise "Erythromycin" futhi "ketoconazole"). Kufanele ukuthi desloratadine akusho ukuthuthukisa umphumela Ethanol phezu CNS.

izincomo ezithile

Yokungezwani komzimba (urticaria, pruritus, ukuqubuka, njll) kubantu abane ezinzima ukungakhuli kwezinso kufanele aphathwe ngokucophelela okukhulu.

Ngokocwaningo olwenziwa, lesi sidakamizwa "Disa" akunamthelela ukuphathwa izimoto nesineke. Kodwa ngaso sonke isikhathi kufanele kukhunjulwe ukuthi akuvamile ukuthuthukisa ukozela kwezinye abantu. Kulokhu, udinga ukuthatha ukunakekelwa okukhethekile ngenkathi ushayela futhi lapho esebenza izakhi eziyinkimbinkimbi.

Izindleko kanye analogue zomuthi

Ngokungafani namanye amanxusa antiallergic, intengo "Sprinkler" izidakamizwa akusilo eliphezulu kakhulu. Thenga le nomuthi kungabangwa ruble 200-350 (10 kanye amaphilisi 30, ngokulandelana).

Ngokuphathelene nozakwabo kubhekwe ezidakamizweni, khona ngobuningi. Nampa: "Lordestin", "Blogir-3", "Aerius" "desloratadine", "u-Eliza," "desloratadine-Teva", "Ezlor" "desloratadine Canon", "Nalorius" "desloratadine-Farmaplant".

Uphenyo yokungezwani komzimba imithi

Izidakamizwa "Disa" - isidakamizwa yokungezwani komzimba engabizi, ezashiya eziningi kokubili Izibuyekezo ezingezinhle futhi omuhle. Iziguli eziningi libike ukuthi imithi kahle lapho zibhekene nomsebenzi. It ngokushesha nangempumelelo ususa yonke izimpawu ukusabela iguliswa, kakhulu ekuthuthukiseni isimo lesiguli.

Abantu abaphuza "Sprinkler" amaphilisi zibonisa ukuthi ukusebenzisa kwabo elula kakhulu. Ngokungafani nezinye izidakamizwa, kubhekwe ngokwanele ukuthatha imithi kanye ngosuku, futhi ungakwazi bayakhohlwa komzimba.

Lokhu nomuthi, kukhona Izibuyekezo ezingezinhle. Iziguli eziningi awukwazi ukuthatha ke, njengoba ngokushesha avele komzimba. Okunjalo iziguli odokotela linqume nemithi ephephile.