Calcium citrate: isici, mshini wezenzo, ukusetshenziswa

Njengoba ingxenye enkulu yomsebenzi Ca esemzimbeni omdala (cishe 99%) eziqukethwe ithambo izicubu ehlanganisa zinhlayiya hydroxyapatite. Ngo serum ezincelisayo eziningi, i-calcium lokuhlushwa imayelana 3 mmol / l (10-12 mg / 100 ml) futhi njalo. iyehla iyenyuka Daily of the constants musa idlule 3-5%. Ca kubalulekile ukusebenza evamile isimiso sezinzwa. I kwamanyuroni synapse calcium ion ukukhuthaza ukukhululwa acetylcholine futhi choline kwakwakhe ne yokwamukela lawo, futhi lapho ivuswe ngu acetylcholine cholinesterase ngokweqile --enzyme hydrolyzes acetylcholine.

Ca ion eziqukethwe reticulum sarcoplasmic, ukukhuthaza ukuxhumana phakathi actin futhi myosin, isb ukunciphisa imisipha zesivikelo sesifuba. Lo mphumela wenziwa khona magnesium ion.

Calcium ion kusebenze izinqubo enzymatic emabangeni kokuqala igazi ekunqandeni - kwetinhlavu thrombin futhi thromboplastin. I yokubopha calcium ion in the oxalate oketshezini olungenambala olusegazini noma citrate kuvimbela igazi ekunqandeni.

Okusanda wazibonakalisa ngendima ekhethekile-calcium kuseli umsebenzi, lapho cytoplasm, emakamu yayo ingeqi 10-6 imvukuzane. Emangqamuzaneni, kukhona eziyisithupha izinqubo eziyisisekelo bokuphila encike lokuhlushwa calcium ion:

a) umsebenzi motor lamaseli (imisipha);

b) excitability lamaseli bayakwazi ukukhiqiza electrostatic isinyathelo engaba (imisipha ithoni, nerve ngiyibona photoreception ukusikwa inhliziyo);

c) uyalulama izinto ukuthi kuhlelwe iseli (uketshezi hormone kanye neurotransmitters);

g) ukufakwa izinto oncibilikayo iseli nganoma vesiculation (phagocytosis);

d) umzimba intracellular (zamagama glucose, lipolysis, njll);

e) ukukhiqizwa kwamangqamuzana (mitosis futhi oocytes kokukhulelwa, isidoda motility).

Ca ion kanye amaprotheni ethize ukunikeza kuyaqina kanye nobulukhuni ithambo. imithi yesimanje isebenzisa amalungiselelo amaningi aqukethe ion -calcium (glyukanat, citrate, chloride, lactate, carbonate, phosphate, njll). Calcium citrate kubaluleke ngokukhethekile. Isigaba eyinhloko calcium ukukhululwa yayo izakhiwo (phosphate, sulfate, chloride) kanye izingxenye organic nokumbiwa ukudla kwenzeka esiswini bedle chloride acid kanye enzyme proteolytic. Carbonic acid wali band acid calcium nosawoti naphakathi esidi isisu kuthiwa ubuhlobo, futhi calcium ifomu ionized noma eziyinkimbinkimbi nge chelates encibilikayo ingena emathunjini amancane. Ngakho-ke, ku-encishisiwe secretory umsebenzi esiswini ukutholakala Ca ukuncela alwanele, kungaba ngesinye sezizathu i-kusilela kwalesi sakhi emzimbeni. Calcium citrate is best ziyoncibilika imvelo azibukhali esiswini. calcium Ionized kalula lingena ulwelwesi begazi, ngisho naphakathi kwezinxushunxushu isithiyo placenta. I ezinkulu okuyingxenye (80%) ye-calcium excreted endleni, umchamo okukhipha labangaba ngu-20%. Ngenxa calcium citrate usawoti kunalokho citrate ikhuthaza ukuncishiswa of oxalate emchamweni, ukusetshenziswa kwezidakamizwa ayimlethelanga kumiswa ezinso.

Litholakala ukuthi ebusuku isebenze ukukhethwa nosawoti wamaminerali kusuka emzimbeni. Ngenxa yokuthi odokotela batusa ukuthatha calcium citrate ntambama noma ebusuku. Wazibonakalisa maqondana negative correlative roomates phakathi umthamo calcium ukulungiselela nomsebenzi ezithaka imithi. Kusho ukuthini? calcium citrate is kangcono amuncwa wumzimba ngemithamo emincane. Ngakho-ke kungcono ukuthatha izidakamizwa izikhathi eziningana ngosuku. Iqembu ngalinye ubudala esungulwe bokuphila calcium ukusetshenziswa kwezinkambiso. Calcium ebekiwe njengoba yokuvimbela nokwelapha (yamathambo, ukukhumuzeka kwamathambo, osteomalacia, lokuqinisa zamazinyo koqweqwe lwawo) njongo. Potassium citrate ezinqunyiwe senhliziyo, umfutho wegazi ophakeme, ukuzinza we acid-base namanzi-usawoti ibhalansi emzimbeni.