Amaphilisi ku ingcindezi "Fiziotenz": Izimpendulo iziguli nodokotela

Ngempumelelo izidakamizwa antihypertensive, a abakhethayo imidazoline yokwamukela agonist buyisidakamizwa "Fiziotenz". Nobufakazi bathi izindlela kusiza ukuphungula ingcindezi abanesifo sikashukela kanye nabantu ngongqimba umzimba okusezingeni eliphezulu.

nomfutho wegazi ophezulu Izici

Izifo izitsha inhliziyo negazi angaphansi eziningi abantu. Nokho, abesifazane lezi ngeziphambeko ukuthuthukisa umhla ezingabantu. Kodwa kwenzeka kuyinkimbinkimbi futhi libhekene abafumana blood pressure, izimpawu ubuhlungu evelele kakhulu. Umfutho ophakeme wegazi njalo ithuthukisa nezinye pathologies: yokukhuluphala, isifo sikashukela, izifo sesibindi nokwehluleka ukusebenza kwezinso lipid umzimba.

Kanye yokwanda kwesisindo emzimbeni kwenzeka ukuphazamiseka Sna, okuyinto imbangela enkulu yokuqothulwa kwehlathi umfutho wegazi ophezulu kanye nomfutho wegazi ophezulu kumiswa. Labelwe lingaze sezinzwa hormone uhlelo neqhaza luminal ukuvaleka imithambo yegazi, okuholela inhliziyo nokulethwa umoya-mpilo ezicutshini futhi izitho kufanele uphushe igazi ukuze torque ngaphansi kwengcindezi okusezingeni eliphezulu, base beba umfutho wegazi ophakeme, yimaphi ama-akhawunti imithi uswidi indlela. Omunye izidakamizwa, okuvumela yokucindezeleka okwandayo lomgwaqo, kuyindlela yokuthola "Fiziotenz".

Sakhiwo Ukwakheka

nomuthi Ikhishwa ngesimo amaphilisi ifilimu-camera. The main asebenzayo izidakamizwa izenzo moksonindin. Izingxenye asizayo zihlanganisa magnesium stearate, crospovidone, povidone, monohydrate-lactose.

izakhiwo kwemithi

Ingqikithi asebenzayo we nomuthi has a central isinyathelo hypotensive. Moxonidine ebuchosheni stem cells ngokukhetha kuvusa receptor sezinzwa, kuhileleke nezinye izinkinga okuyinto e ukulawulwa tonic reflex futhi lingaze isimiso sezinzwa. Imiphumela iba yinhlanganisela yokukhandleka ukwehla umsebenzi futhi lingaze neuropathy lwemithambo ingcindezi. Ukuhlola okuhlukahlukene (placebo-elawulwa, olwenziwa, kabili izimpumputhe) ukufakazela ukuphumelela izidakamizwa "Fiziotenz". Izibuyekezo iziguli ukuqinisekisa ukuthi izidakamizwa kuyehluka kuneminye sympatholytic ejenti antihypertensive ukuthi akavumi ukuba nomlomo owomile, lapho isetshenziswa akukho ukupholisa.

Pharmacodynamics futhi Pharmacokinetics

Ngemva eyamukelayo kwangaphakathi kusho amaphesenti 90 ugxile kusukela uhlelo gastro-emathunjini. Ubuningi esiphezulu we ketshezi asebenzayo oketshezini olungenambala lwegazi is ebonwe ihora. Sakusihlwa ngosuku pharmacokinetics ka moxonidine akunamthelela.

I ezinkulu metabolite kwakwakhe esebenzayo dehydrogenated moxonidine futhi guanidine nemikhiqizo. Isigamu-ukuphila moxonidine kwenzeka ngaphakathi kwamahora angu-2.5 kanye ngosuku ngo-90% okukhipha isici ngokusebenzisa izinso namathumbu.

In iziguli nge nomfutho wegazi ophezulu, uma kuqhathaniswa nabantu enempilo, izinguquko pharmacokinetics ka moxonidine beziphawuleka. Kancane imingcele kinetic zingaguqulwa ezigulini esezikhulile lihlotshaniswa kuncipha moksodinina umfutho umzimba, kanye bioavailability yayo ephakeme. Ngenxa yokuntuleka izifundo pharmacokinetic is hhayi Kunconywa ukuba asebenzise izidakamizwa ukuze iziguli lokuya ebudaleni.

Izidakamizwa "Fiziotenz" Iziyalezo yokusetshenziswa

Nobufakazi bathi Amakhambi kumele kuthathwe ngomlomo, kungakhathaliseki ukusetshenziswa ukudla. Ngokuvamile, izidakamizwa isetshenziswa umthamo kokuqala nsuku 200 mcg. Umkhawulo lemali eyodwa izidakamizwa kumele singeqi micrograms 400 lemali nsuku zonke ehlukaniswa izinyathelo ezimbili - 600 micrograms. Iziguli ngokulinganisela ezinzima inhliziyo ukwehluleka abaku- hemodialysis, kutuswa ukuthatha micrograms 200 ngosuku kusho. Nge ezinhle ukubekezelelana nenani lomuthi kungase kukhule kabili.

ukweqisa izidakamizwa

Uma ukusetshenziswa okweqile izimpawu ezihlukahlukene negative kungenzeka izidakamizwa. Ngakho, izibhebhe ezazisezandleni "Fiziotenz" ingcindezi (izibuyekezo zisikisela) kungase kubangele ubuhlungu bekhanda, ukozela, ukupholisa. Lapho umthamo idlula ingcindezi lingase lehle kakhulu, singakwazi ukuhlakulela ubuhlungu epigastric waphawula xerostomia, bradycardia, ukuhlanza, ukukhathala, ukukhathala anda, isiyezi. Ngaphezu kwalokho, iziguli kungenzeka ukhathazekile Hyperglycemia, tachycardia, futhi ukwanda lezivakashi e ingcindezi.

sinqobe ethize zenzelwe ukwelashwa izimpawu yokweqisa. Uma hypotension Kufanele ufake Dopamine futhi ukwandisa okuqukethwe uketshezi emzimbeni. Izimpawu bradycardia kungenzeka ukuba ayeke usebenzisa atropine. Ngo ukweqisa izidakamizwa ekunciphiseni noma ekuqedeni nakuba umfutho wegazi ophakeme emithanjeni Kunconywa ukusetshenziswa kwe-alpha-adrenoceptor abantu abamelene nani.

izidakamizwa ekuhlanganyeleni

Inhlanganisela izidakamizwa akusho ngaso sonke isikhathi ukunikeza ukubaluleka ngenxa. Nokho, lapho ethola izidakamizwa ezimbili noma ngaphezulu kungenzeka lube buthaka noma ukuqinisa yezenzo mutual. Esimweni sokuqala, umuthi ngeke kube yi kulindeleke, e isimo yesibili, kukhona ingozi ukweqisa izidakamizwa, ngisho ushevu.

Ngakho, uma isetshenziswa izidakamizwa antihypertensive (isisu thiazide, i-calcium blocker iziteshi kancane) kanye nomuthi "Fiziotenz" (izibuyekezo ukuxwayisa ngale) angagcina hypotensive okufakiwe umphumela. ukwelashwa Ngesikhathi antidepressant tricyclic kwehlisa ukusebenza central protivopertenzivnyh izidakamizwa, futhi akufanele isetshenziswe kanye izidakamizwa "Fiziotenz".

Ngaphezu kwalokho, ithuluzi ikuvumela ukuba ngcono umsebenzi engqondweni yethu in iziguli buthaka ngokuthatha izidakamizwa "Lorazepam". Isicelo kanye benzodiazepines kungadala ukupholisa ethuthukisiwe. Ekumisweni izidakamizwa "Digoxin", "glibenclamide", "hydrochlorothiazide" akukho ukuxhumana pharmacokinetic.

Sebenzisa ngesikhathi sokukhulelwa

izidakamizwa abahlukahlukene zibulale umbungu noma umbungu, okuholela ezimweni ezithile ukuze izenzo ezimbi ingane. Njengoba izingxenye izidakamizwa ethathwe ubisi lukamama, angase awele umzimba kwezinsana ngokuvumelana naso. Ngakho-ke, phakathi nokukhulelwa kanye lactation, kubalulekile ukuthatha imithi ngokucophelela okukhulu.

Iyathinteka - kanye izidakamizwa "Fiziotenz". Ukhetho lwakhe isebenza kuphela emva kokubonisana onguchwepheshe, enesisindo ngokucophelela inzuzo ezingase zisetshenziselwe ukuba ngumama ukulinyazwa ingane. Kusukela isithako ludlulele ngaphakathi ubisi lwebele ngesikhathi ukunceliswa kwabantwana kufanele uhlukane nale isicelo yayo noma ukumisa ibele.

izifundo kokulinganisa olwenziwe izilwane, umphumela ngokuqondile noma ngokungaqondile zomuthi ku sokukhulelwa, fetus (embryonic) noma ukuthuthukiswa nangemuva kokuzalwa komntwana baye abaziwa.

isicinganani

Thanda imithi kakhulu, amaphilisi "Fiziotenz" (izibuyekezo ukusekela lokhu) ebangela ukusabela okungekuhle kusuka emzimbeni. Lokhu kujwayele ukwenzeka uma usebenzisa amanani esiphezulu isikhathi eside futhi hypersensitive ukuze isithako esebenzayo.

Isimiso sezinzwa kuyinto ukusetshenziswa kwezidakamizwa iyaphendula ubuhlungu bekhanda, ukozela noma ukuqwasha, isiyezi. Lezi zimpawu zibonakala njalo ngokwanele. On the ingxenye inhliziyo futhi semithambo uhlelo ukusabela ezingezinhle zenzeka ezimweni ezingavamile, livezwa iconsi elibukhali ingcindezi, hypotension orthostatic. Ngaphezu kwalokho, iziguli emva umlomo ekuphathweni isipiliyoni ezomile, isicanucanu, zingase waphawula njengoba ukusabela dermatologic angioedema, pruritus noma ukuqubuka. Uma kukhona side effect zomuthi akufanele wayeka, izimpawu ezingezinhle ngemva kwamasonto amathathu ukusetshenziswa, ithambekele zinyamalale. Nokho, uthintane onguchwepheshe sisadingeka.

Izimo

Akathembisi ikhambi "Fiziotenz" ingase ikhishwe kuzo zonke izimo. Uphenyo odokotela bathi kunconywa hhayi ukuthatha imithi ngesikhathi:

• bradycardia (kwenhliziyo Me 50 amabhithi ngeminithi);
• Sss;
• lezinceku galactose malabsorption noma ukungabekezelelani (glucose)
• ukuntula lactase;
• ukuzwela anda ukuze izindlela ingxenye;
• izingane nentsha eneminyaka engaphansi kwengu-iningi.

Okumele kuqashelwe ebekiwe izidakamizwa esigabeni ukugcina noma ukwehluleka ezinzima kwezinso, iziguli abaku- hemodialysis, ukuhluleka ezinzima isibindi.

Tablets "Fiziotenz": izinkomba ukusetshenziswa, ukubuyekezwa, imiyalelo ezikhethekile

Imiphumela yaloku kuhlola okungenhla Primary, lapho odokotela akunikeze imithi kuba nomfutho wegazi ophezulu. Kumele kukhunjulwe ukuthi ngesikhathi yokwelapha kudingeka afeze ukuqapha esihleliwe isimo blood pressure, ECG nokushaya kwenhliziyo. Uma ufuna ukukhansela imithi ke lokhu kufanele kwenziwe kancane kancane.

Umkhiqizo akuphazamisi ikhono ukushayela futhi izindlela zokuhamba. Nokho, ekwakhiweni "Fiziotenz" (kobufakazi nesineke ukhombe ke) kufanele athathe ngokuqapha ngoba kungabangela nesiyezi futhi ukozela. Leli qiniso kufanele kubhekwe abantu behileleka enobungozi, odinga ukujula njalo, imisebenzi.

izimo Isitoreji, analogs futhi intengo

Tablets kufanele igcinwe endaweni lapho izingane zingenakuwafinyelela. Angaphansi kwemithetho yesitoreji (lokushisa kuze kube degrees 25 C, Okomileyo endaweni emnyama) izidakamizwa ngeke ulahlekelwe izakhiwo zabo kwemithi, iminyaka emibili. Thenga imithi "Fiziotenz" (izibuyekezo siliqinisekise) kungenzeka on kadokotela Pharmacy. Inani isembozo amaphilisi (0.2 mg) kuyinto ruble 275. Uma imithi ekhemisi ngasizathu simbe wayengekho, kubalulekile ukubheka ontanga: "UCynthia," "Moksoniteks", "Moxonidine", "Moksogammu".

Izibuyekezo sokulungiselela "Fiziotenz"

Iziguli eziningi ezikhuluma ngayo izidakamizwa njengoba izindlela eziphumelelayo izinga. Abantu bathi nokuyiphuza imishanguzo kuze kuphele iminyaka, umuthi kwehlisa umfutho wegazi muhle, kungekho engemihle. Ezinye ubheke amaphutha amaphilisi zibiza "Fiziotenz". Izibuyekezo kubonisa ukuhambisana omuhle nezinye izindlela imithi abanomfutho wegazi ophakeme.