"Clonazepam": ukubuyekezwa. "Clonazepam": yokusetshenziswa, side effects

"Clonazepam" - izidakamizwa antiepileptic esiphathelene benzodiazepine nemikhiqizo. Ngemva kokuthola lezi "clonazepam" Izilinganiso kwesokunxele izidakamizwa ikakhulukazi omuhle. Umuthi has imisipha relaxant nemiphumela okulalisayo, kodwa futhi kuba nomphumela okulalisayo.

Ukwakheka, ifomu ukukhululwa "clonazepam" izidakamizwa

Umuthi itholakala amaphilisi nge okuqukethwe ezahlukene yezingxenye esemqoka:

• 0.5 mg. Ngaphezu clonazepam, isakhiwo kuhlanganisa monohydrate-lactose. Ukuze izithako amaphilisi osebenza sodium carboxymethylstarch. "Clonazepam" amaphilisi aqukethe magnesium stearate, gelatine. Nezinsizasenzo nazo talc futhi amazambane isitashi. amaphilisi Color enamathiselwe udayi E110.

• 2 mg. izithako engeziwe asizayo - polysorbate 80, monohydrate-lactose. Ukwakheka izidakamizwa samanje carboxymethylstarch sodium ne-sodium lauryl sulphate. talc, gelatin izithako ozikhethela. izingxenye Asizayo futhi basonta nezinye izinto - magnesium stearate, irayisi, amazambane isitashi.

isinyathelo kwemithi "clonazepam" izidakamizwa

"Clonazepam" umphumela ezicindezelayo ezikuyi-inani elikhulu izakhiwo ezakha uhlelo sezinzwa, ikakhulu labo abahlobene ukusebenza ngokomzwelo. Umthelela lesi sidakamizwa "clonazepam" imfundo manual, impendulo uboniswa njengendlela okulalisayo, anxiolytic futhi okuyiluthayo (zokugcina ngokulinganisela uzwakalise). I nomuthi kunciphisa lwamathambo imisipha ithoni, kuvimbela generalized nokuquleka convulsive. Kukhona nethonya elihle inkambo ukuhlaselwa sokuwa (ebalulekile, generalized).

Pharmacokinetics

Umuthi amuncwa umzimba cishe ngokuphelele pheshana emathunjini is ngokukhishwa ngokuyinhloko izinso (metabolites), ingane ingxenye (2%) ubonakala zinjalo. Inqubo kuthatha isigamu-ukuphila amahora 20 kuya 40. I bioavailability sokulungiselela udle 90%, ubuhlobo igazi eligciniwe - 85%, emakamu eliphakeme ifinyelele kusho 2.5 amahora. Ekwelapheni "clonazepam" izingxenye zalo singene ubisi lwebele.

Izinkomba ukusetshenziswa zomuthi

Tablets "clonazepam" ezifanelekela nokwelashwa kweziguli zobudala obuhlukene abanesifo sokuwa, kungakhathaliseki zako:

• ukuquleka esinqunyiwe (zendawo, ebalulekile) wanoma iyiphi degree of kobukhulu;
• izimo convulsive (tonic, clonic);
• ukuquleka elula okwesibili generalized;
• usuke ungekho atypical (Lennox-Gastaut syndrome);
• ukuquleka myoclonic;
• ejwayelekile ukungabi ukuquleka;
• ukuquleka tonic-clonic ukubonakaliswa zamabanga aphansi naphezulu.

"Clonazepam" okunqunyiwe ukunciphisa imisipha ithoni, kokubili okuyiluthayo zinhlekelele futhi lengqondo ngesikhatsi ukwelashwa.

Ukusetshenziswa kwezidakamizwa "clonazepam"

Umthamo edingekayo kunqunywa kuzinto eziningi. Ngesikhathi besanda kuqala yokwelapha isebenzisa umthamo encane "clonazepam" (0.5 mg), kancane kancane ekushintsheni Isikali kuze umphumela oyifunayo eyatholakala. Ngesikhathi esifanayo idlule umthamo esiphezulu akuvunyelwe. Njengoba nokubuyekezwa, "clonazepam" ayikwazi evele waphakamisa ngisho nalapho ukuphathwa yaba ngeyesikhashana. ukwenqatshwa Cijela zomuthi okusongelayo ukuthuthukiswa i kokuquleka sokuwa.

Ukwamukelwa isithuthwane:

• Abadala. ukwelashwa kokuqala is ezenziwe usebenzisa ayibi ngaphezu kuka-1 mg izidakamizwa. Umthamo ibalwa ngelanga, ihlukaniswe 3 noma 4 ngemithamo, okufanele kwenziwe njalo ngezikhawu ezithile. Ngaphandle ikhono lokusebenzisa izidakamizwa ngemithamo alinganayo, inxenye enkulukazi "clonazepam" isiphuzo ngaphambi kokulala. Ngokuvamile, ngezilinganiso ezanele nsuku zonke ku ezahlukene 4 kuya kwezingu-8 mg izidakamizwa. Umthamo yesondlo kumele singeqi 20 mg (izuzwe ngesikhathi amasonto 2-4 yokwelapha). Lapho kunqunywa umthamo ngempumelelo nsuku zonke, okuvumela ukuba silondoloze isimo evamile yomzimba, it ovunyelwe umthamo owodwa ngesikhathi sokulala.
• Izingane (ngesisindo sezinti okungenani 30 kg). Njengoba nokubuyekezwa, "clonazepam" ekuqaleni kuboniswe izingane 0.5 mg ukunquma umthamo yayo elilungile.

Reception sifo, okuyinto kuhambisana ubuhlungu paroxysmal:

• Abadala. Okokuqala, iziguli iqondiswa 1-2 ngosuku nokushintsha kokudla nokufakwa (0.5 mg isikhathi ngasinye). Iziguli eziningi umthamo eyanele zokwelapha 1 mg / usuku. Usuku angeke baphuze ezingaphezu kuka-1 mg izidakamizwa "clonazepam". Nokho, ku-, bonisa ukuthi kwezinye izimo, odokotela kungase kwandise umthamo ukuze 4 mg. Ezimweni ezinjalo, umthamo kancane kancane washintsha (ububanzi - 3 izinsuku, kungenzeka unezela 0.5 mg). Uma ufuna ukunciphisa ububi besimo sokuguquka ukozela emini, umthamo ibalwa edilini lomshado emini, ungakwazi kudla ngaphambi sokulala.
• Izingane. Ezigulini abangekho abaneminyaka engaphezu kuka-18, lo ukuthola of the izidakamizwa syndrome zingase ingase ingaphumeleli futhi ezingaphephile.

Ukuze ugweme nanoma yiziphi izinkinga, lesi sidakamizwa "clonazepam" izibuyekezo odokotela batusa ukuthatha ngokuqinile phezu izincomo onguchwepheshe ngubani ekwelapheni.

Izimo ethola "clonazepam" izidakamizwa

Tablets azisetshenziswa lapho lenyuka kuvelana izinto kusukela lapho yakhiwa. Umuthi is contraindicated kulezi uthi:

• myasthenia gravis;
• ukungakhuli ukwazi;
• abantwana, ibele;
• glaucoma (Ukuvalwa);
• iziyaluyalu zokuphefumula kokuba umsuka emaphakathi, ezinzima esingamahlalakhona zokuphefumula;
• Heavy ageleza kwezinso futhi ukwehluleka hepatic;
• kuwukubonakaliswa elele singathatha syndrome;
• utshwala ubuthi;
• porphyria ifomu oyingozi.

Imiphumela emibi "clonazepam" izidakamizwa

Cabangela imiphumela emibi, okungase kubangele "clonazepam". Ukusebenzisa izidakamizwa kungenzeka ukuthi umataniswe nge ukusabela ezingezinhle. Kungadala ukucobeka, isicanucanu ukucasuka. Uma ukusabela ngu umzimba womuntu Ufika bakhathala ngokushesha, ubelokhu ukudidiyelwa ukunyakaza. Ukuze wehlise umphumela ukubonakaliswa yemiphumela emibi, okokuqala udinga ukusebenzisa umthamo ezincane, kancane kancane zandise izinto kuze kuba elilungile.

Kuyaziwa ukuthi phakathi ukwelashwa "clonazepam" kusho ulisebenzise kokunikezwa kwe-izincomo kungabangela ukweqisa izidakamizwa ezaziwayo. Ezimweni ezinjalo, kukhona okuhle, okungaholela ukudideka, stupor, okungase kuholele ekungasebenzini equlekile. Phakathi kwezinye izimpawu - nciphisa semithambo, ukuphefumula kahle, ukozela. Kuyadingeka ukugeza isisu (ngempumelelo ngokushesha ngemuva kokudla amaphilisi) ukuqhuba yokwelapha ezifanele. Kubalulekile ukuqapha njalo izinguquko izinkomba ezifana blood pressure, ishayela, ukuphefumula. Kwezinye izimo, kudingeka ukuqaliswa ukupholisa lokukhanda. Kukhona alikaziwa ikhambi lobuthi bama - "Flyumazenil," kodwa asifanele ukuphatha iziguli belashwa "clonazepam" isikhathi eside.

Akubalulekile ukuba sihlanganise "clonazepam" kanye notshwala. Izibuyekezo ukuvumela ukuqinisekisa ukuthi inhlanganisela enjalo singaba usongo ekuphileni. Kuyefana nasendleleni zonke izidakamizwa ukuthi isinyathelo isimiso sezinzwa esiyinhloko, ezivimbela umsebenzi walo.

Izidakamizwa ukuxhumana "clonazepam" ukulungiselela

Umthelela imithi ukwandisa analgesics kwezidakamizwa, anticonvulsants. Umphumela efanayo siyenzeka ngokuhlanganisa ngayo antidepressant, neuroleptics, barbiturates, futhi lapho kuhlangene utshwala izinto inciphe lwamathambo imisipha ithoni. Ngempumelelo yokuphathwa kuyehla uma udle i-nicotine.

Izindleko, ukubuyekezwa mayelana izidakamizwa "clonazepam"

Thenga "clonazepam" amaphilisi e Moscow kungabangwa ruble 97-150. (30 nama-PC.). Umuthi ngempumelelo yisithuthwane ngokulandelana kwawo, uma kuhlangatshezwene nakho izincomo kadokotela. Lapho nokuquleka atonic kungaba izinyanga ezimbili, isikhathi yokwelapha kumanele isikhathi esinjalo, ungashintsha ekwelashweni yesondlo. Ngezinye izikhathi kunemiphumela emibi, kodwa ikakhulu kuphela esigabeni sokuqala ukwelashwa, ngokuvamile ubuthakathaka.

Ukwahlulela ngokubukeka ulwazi aqukethe ukubuyekezwa, "clonazepam" kuqeda anda imisipha ithoni e cishe amasonto amathathu. Odokotela bangase akunikeze imithi uma alamu, ukwesaba, IRR, okuyinto kuhambisana uvalo. Umuthi siyasebenza, usebenza ngokushesha.

Izibuyekezo "clonazepam" ibonakala njengendlela yokuthola okuhle ukuthi wenza umsebenzi walo, kodwa kungaholela impilo ebuthaka (ubuthakathaka, ukukhathala, nokunye. P.).