Analogue "Diflucan" - kusho "fluconazole"

Analogue "Diflucan" - kusho "fluconazole" - iyi-ejenti antifungal nemphumela ethize kakhulu. Umuthi uyakwazi ekuvimbeni umsebenzi ezinye enzyme, zivimbela ukuguqulwa of lanosterol ukuze ergosterol. Ngaphezu kwalokho, izidakamizwa kwandisa permeability of cell ulwelwesi, ekuvimbeleni ukufanisana futhi ukukhula kwamagciwane. Umuthi siyasebenza izifo fungal ezingosomathuba cuphuluza isikhunta bohlobo Candida, kuhlanganise generalized kwamasosha omzimba izinhlobo candidiasis enhlabathini. Nge imithi ngomlomo has absorbability ezinhle. Ngesilinganiso ukumuncwa ayitsintseki ukudla. I bioavailability zomuthi imayelana 90%. okuqukethwe Maximum egazini ifinyelela ikhambi kumaminithi 30-90. Umuthi is kahle kwasakazwa kwezicubu nasoketshezini ukungena ubisi. Kumele wathi ukuthi inani lentengo lomuthi "fluconazole" umyalo ezidlula ngaphansana ukubaluleka "Diflucan" (esikhathini esidlule kuyodingeka bakhokhe engama-ruble, anamakhulu mane ukuba emakhulu asibhozo).

ubufakazi

Medicine "fluconazole" (analogue "Diflucan") inikezwa e-cryptococcal meningitis, cryptococcosis nezinye kwasendaweni ukutheleleka cryptococcal in iziguli impendulo evamile omzimba bese nezinhlobo ezahlukene kwamasosha omzimba. Ngu ubufakazi candidiasis zihlanganisa uhlobo generalized, candidiasis eqonda, candidemia, nezinye izinhlobo izifo koda kubangelwa ukhunta Candida. Umuthi Kunconywa nokuvimbela izifo fungal in iziguli izimila abulalayo yohlamvu. ejenti esiwabelwe mycosis izinyawo, imbilapho, esifubeni.

Umthamo lwemithi

Analogue "Diflucan" - kusho "fluconazole" - anqunyiwe iziguli iminyaka eyishumi nanhlanu ngesikhathi mass enkulu kuka-50 kg. Lapho izifo cryptococcal ka kwasendaweni ezahlukene ngosuku lokuqala kusihlwa umthamo mg 400. Ngemva kwalokho, inani nomuthi sehliselwe 200 mg ngosuku. Isikhathi yokwelapha kulezi pathologies incike nekusebenta ukwelashwa, okuyinto kuqinisekiswa izifundo mycological. Isicelo cryptococcal meningitis kufanele kuhlale okungenani amasonto ayisithupha ukuba eyisishiyagalombili. Lapho eqonda candidiasis, candidemia, nezinye izinhlobo koda Candida izifo ngosuku lokuqala inani izidakamizwa - 400 mg, umthamo kuyehla kube mg 200. Endabeni ka ukusebenza enganele ukwelashwa umthamo luyanda emuva mg 400. Isikhathi ukwelashwa incike ukuphumelela izindlela.

isicinganani

Analogue "Diflucan" - lesi sidakamizwa "fluconazole" - kungabangela nesiyezi, ubuhlungu ekhanda, emzimbeni, ubuhlungu besisu, inhliziyo yakhe imnyama, isicanucanu. Ngesisekelo ukwelashwa kungakusiza ukuthuthukisa thrombocytopenia, nokungezwani komzimba nezinto ezifana ukuvuvukala ebusweni, epidermal necrolysis anobuthi, isikhumba ukulunywa. amaphilisi Analogs kungabangela ukuphazamiseka isibindi, izinso, hypokalemia, hypertriglyceridemia.

Izimo

Musa linqume izidakamizwa ngaphambi kweminyaka eli-4, uma ukungabekezeleli izingxenye zalo. Contraindicated ukusetshenziswa kuhlangene nomuthi "Terfenadine", "Astemizole" nezinye iqhaza ukuze yokwandisa iminyaka qt-isikhawu. Isexwayiso phakathi ukwelashwa nge show nezici ezithile ukuze pathologies leyehlukile (electrolyte ukungalingani, organic isifo senhliziyo, njll).